Comparison of Multiple Displacement Amplification (MDA) and Multiple Annealing and Looping-Based Amplification Cycles (MALBAC) in Limited DNA Sequencing Based on Tube and Droplet

Comparison of Multiple Displacement Amplification (MDA) and Multiple Annealing and Looping-Based Amplification Cycles (MALBAC) in Limited DNA Sequencing Based on Tube and Droplet

Whole genome amplification (WGA) is crucial for whole genome sequencing to investigate complex genomic alteration at the single-cell or even single-molecule level. Multiple displacement amplification (MDA) and multiple annealing and looping based amplification cycles (MALBAC) are two most widely app...

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Bibliographic Details
Main Authors: Xiaoxiang Zhou, Ying Xu, Libo Zhu, Zhen Su, Xiaoming Han, Zhen Zhang, Yan Huang, Quanjun Liu
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Micromachines
Subjects:
whole genome amplification
droplets
multiple displacement amplification
multiple annealing and looping based amplification cycles
Online Access:https://www.mdpi.com/2072-666X/11/7/645

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