Targeting Adenosine Receptors for the Treatment of Cardiac Fibrosis
Adenosine is a ubiquitous molecule with key regulatory and cytoprotective mechanisms at times of metabolic imbalance in the body. Among a plethora of physiological actions, adenosine has an important role in attenuating ischaemia-reperfusion injury and modulating the ensuing fibrosis and tissue remo...
Main Authors: | Elizabeth A. Vecchio, Paul J. White, Lauren T. May |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2017-05-01
|
Series: | Frontiers in Pharmacology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/article/10.3389/fphar.2017.00243/full |
Similar Items
-
New perspectives in signaling mediated by receptors coupled to stimulatory G protein: the emerging significance of cAMP efflux and extracellular cAMP-adenosine pathway.
by: Rosely Oliveira Godinho, et al.
Published: (2015-03-01) -
Extracellular cAMP-Adenosine Pathway Signaling: A Potential Therapeutic Target in Chronic Inflammatory Airway Diseases
by: Enio Setsuo Arakaki Pacini, et al.
Published: (2022-04-01) -
Complex formation and functional interaction between adenosine A1 receptor and type-1 metabotropic glutamate receptor
by: Yuji Kamikubo, et al.
Published: (2015-07-01) -
The different effects of four adenosine receptors in liver fibrosis
by: Lan Yang, et al.
Published: (2024-09-01) -
New heterocyclic A1/A3 adenosine receptor ligands through molecular simplification strategies
by: Letizia Crocetti, et al.
Published: (2025-04-01)