Adapting Genotyping-by-Sequencing and Variant Calling for Heterogeneous Stock Rats

Adapting Genotyping-by-Sequencing and Variant Calling for Heterogeneous Stock Rats

The heterogeneous stock (HS) is an outbred rat population derived from eight inbred rat strains. HS rats are ideally suited for genome wide association studies; however, only a few genotyping microarrays have ever been designed for rats and none of them are currently in production. To address the ne...

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Bibliographic Details
Main Authors: Alexander F. Gileta, Jianjun Gao, Apurva S. Chitre, Hannah V. Bimschleger, Celine L. St. Pierre, Shyam Gopalakrishnan, Abraham A. Palmer
Format: Article
Language:English
Published: Oxford University Press 2020-07-01
Series:G3: Genes, Genomes, Genetics
Subjects:
genotyping-by-sequencing
heterogeneous stock
rat
imputation
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.120.401325

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