Inhibiting Matrix Metalloproteinase by Cell-Based Gene Transfer Effectively Treats Acute and Chronic Ischemic Cardiomyopathy
After a myocardial infarction (MI), an increase in the cardiac ratio of matrix metalloproteinases (MMPs) relative to their inhibitors (TIMPs) causes extracellular matrix modulation that leads to ventricular dilatation and congestive heart failure. Cell therapy can mitigate these effects. In this stu...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2012-05-01
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| Series: | Cell Transplantation |
| Online Access: | https://doi.org/10.3727/096368911X601000 |