Inhibiting Matrix Metalloproteinase by Cell-Based Gene Transfer Effectively Treats Acute and Chronic Ischemic Cardiomyopathy

Inhibiting Matrix Metalloproteinase by Cell-Based Gene Transfer Effectively Treats Acute and Chronic Ischemic Cardiomyopathy

After a myocardial infarction (MI), an increase in the cardiac ratio of matrix metalloproteinases (MMPs) relative to their inhibitors (TIMPs) causes extracellular matrix modulation that leads to ventricular dilatation and congestive heart failure. Cell therapy can mitigate these effects. In this stu...

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Bibliographic Details
Main Authors:	Hai Tian M.D., Ph.D., Ming-Li Huang, Kai-Yu Liu, Zhi-Bo Jia, Lu Sun, Shu-Lin Jiang, Wei Liu, Heather Y. Mcdonald Kinkaid, Jun Wu, Ren-Ke Li M.D., Ph.D.
Format:	Article
Language:	English
Published:	SAGE Publishing 2012-05-01
Series:	Cell Transplantation
Online Access:	https://doi.org/10.3727/096368911X601000

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