Eosinophilic Solid and Cystic Renal Cell Carcinoma: From Unclassified to Classified, A Case Report
Eosinophilic solid and cystic renal cell carcinoma (ESC RCC) is a novel tumour with unique morphological and immunohistochemical features. It is a recently described entity after the 2016 World Health Organization Classification of Tumours of the Urinary System and Male Genital Organs and is charact...
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Format: | Article |
Language: | English |
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Federation of Turkish Pathology Societies
2022-01-01
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Series: | Türk Patoloji Dergisi |
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http://www.turkjpath.org/pdf.php3?id=1968
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author | Rashim SHARMA Balamurugan THIRUNAVUKKARASU Poonam ELHENCE Mahaveer Singh RODHA Binit SUREKA |
author_facet | Rashim SHARMA Balamurugan THIRUNAVUKKARASU Poonam ELHENCE Mahaveer Singh RODHA Binit SUREKA |
author_sort | Rashim SHARMA |
collection | DOAJ |
description | Eosinophilic solid and cystic renal cell carcinoma (ESC RCC) is a novel tumour with unique morphological and immunohistochemical features. It is a recently described entity after the 2016 World Health Organization Classification of Tumours of the Urinary System and Male Genital Organs and is characterised by a solid cystic tumour composed of polygonal cells with voluminous eosinophilic cytoplasm and CK20 positivity. This tumour has uncertain malignant potential and also has an association with tuberous sclerosis complex (TSC). Sarcomatoid differentiation has not been reported in ESC RCC till now. ESC RCC poses a diagnostic challenge as many eosinophilic/oncocytic renal tumours are included in the differentials. We present a case of ESC RCC with sarcomatoid differentiation in an elderly female without any clinical features of TSC and discuss the differential diagnosis of oncocytic renal tumours. |
first_indexed | 2024-04-10T10:23:05Z |
format | Article |
id | doaj.art-3aa52b68ebb440369287bed9ff4f5dda |
institution | Directory Open Access Journal |
issn | 1018-5615 1309-5730 |
language | English |
last_indexed | 2024-04-10T10:23:05Z |
publishDate | 2022-01-01 |
publisher | Federation of Turkish Pathology Societies |
record_format | Article |
series | Türk Patoloji Dergisi |
spelling | doaj.art-3aa52b68ebb440369287bed9ff4f5dda2023-02-15T16:21:29ZengFederation of Turkish Pathology SocietiesTürk Patoloji Dergisi1018-56151309-57302022-01-0138106006510.5146/tjpath.2021.01531Eosinophilic Solid and Cystic Renal Cell Carcinoma: From Unclassified to Classified, A Case ReportRashim SHARMABalamurugan THIRUNAVUKKARASUPoonam ELHENCEMahaveer Singh RODHABinit SUREKAEosinophilic solid and cystic renal cell carcinoma (ESC RCC) is a novel tumour with unique morphological and immunohistochemical features. It is a recently described entity after the 2016 World Health Organization Classification of Tumours of the Urinary System and Male Genital Organs and is characterised by a solid cystic tumour composed of polygonal cells with voluminous eosinophilic cytoplasm and CK20 positivity. This tumour has uncertain malignant potential and also has an association with tuberous sclerosis complex (TSC). Sarcomatoid differentiation has not been reported in ESC RCC till now. ESC RCC poses a diagnostic challenge as many eosinophilic/oncocytic renal tumours are included in the differentials. We present a case of ESC RCC with sarcomatoid differentiation in an elderly female without any clinical features of TSC and discuss the differential diagnosis of oncocytic renal tumours. http://www.turkjpath.org/pdf.php3?id=1968 eosinophilic solid and cystic renal cell carcinomaunclassified renal cell carcinomaemerging entityoncocytic renal tumour |
spellingShingle | Rashim SHARMA Balamurugan THIRUNAVUKKARASU Poonam ELHENCE Mahaveer Singh RODHA Binit SUREKA Eosinophilic Solid and Cystic Renal Cell Carcinoma: From Unclassified to Classified, A Case Report Türk Patoloji Dergisi eosinophilic solid and cystic renal cell carcinoma unclassified renal cell carcinoma emerging entity oncocytic renal tumour |
title | Eosinophilic Solid and Cystic Renal Cell Carcinoma: From Unclassified to Classified, A Case Report |
title_full | Eosinophilic Solid and Cystic Renal Cell Carcinoma: From Unclassified to Classified, A Case Report |
title_fullStr | Eosinophilic Solid and Cystic Renal Cell Carcinoma: From Unclassified to Classified, A Case Report |
title_full_unstemmed | Eosinophilic Solid and Cystic Renal Cell Carcinoma: From Unclassified to Classified, A Case Report |
title_short | Eosinophilic Solid and Cystic Renal Cell Carcinoma: From Unclassified to Classified, A Case Report |
title_sort | eosinophilic solid and cystic renal cell carcinoma from unclassified to classified a case report |
topic | eosinophilic solid and cystic renal cell carcinoma unclassified renal cell carcinoma emerging entity oncocytic renal tumour |
url |
http://www.turkjpath.org/pdf.php3?id=1968
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