Eosinophilic Solid and Cystic Renal Cell Carcinoma: From Unclassified to Classified, A Case Report

Eosinophilic solid and cystic renal cell carcinoma (ESC RCC) is a novel tumour with unique morphological and immunohistochemical features. It is a recently described entity after the 2016 World Health Organization Classification of Tumours of the Urinary System and Male Genital Organs and is charact...

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Main Authors: Rashim SHARMA, Balamurugan THIRUNAVUKKARASU, Poonam ELHENCE, Mahaveer Singh RODHA, Binit SUREKA
Format: Article
Language:English
Published: Federation of Turkish Pathology Societies 2022-01-01
Series:Türk Patoloji Dergisi
Subjects:
Online Access: http://www.turkjpath.org/pdf.php3?id=1968
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author Rashim SHARMA
Balamurugan THIRUNAVUKKARASU
Poonam ELHENCE
Mahaveer Singh RODHA
Binit SUREKA
author_facet Rashim SHARMA
Balamurugan THIRUNAVUKKARASU
Poonam ELHENCE
Mahaveer Singh RODHA
Binit SUREKA
author_sort Rashim SHARMA
collection DOAJ
description Eosinophilic solid and cystic renal cell carcinoma (ESC RCC) is a novel tumour with unique morphological and immunohistochemical features. It is a recently described entity after the 2016 World Health Organization Classification of Tumours of the Urinary System and Male Genital Organs and is characterised by a solid cystic tumour composed of polygonal cells with voluminous eosinophilic cytoplasm and CK20 positivity. This tumour has uncertain malignant potential and also has an association with tuberous sclerosis complex (TSC). Sarcomatoid differentiation has not been reported in ESC RCC till now. ESC RCC poses a diagnostic challenge as many eosinophilic/oncocytic renal tumours are included in the differentials. We present a case of ESC RCC with sarcomatoid differentiation in an elderly female without any clinical features of TSC and discuss the differential diagnosis of oncocytic renal tumours.
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spelling doaj.art-3aa52b68ebb440369287bed9ff4f5dda2023-02-15T16:21:29ZengFederation of Turkish Pathology SocietiesTürk Patoloji Dergisi1018-56151309-57302022-01-0138106006510.5146/tjpath.2021.01531Eosinophilic Solid and Cystic Renal Cell Carcinoma: From Unclassified to Classified, A Case ReportRashim SHARMABalamurugan THIRUNAVUKKARASUPoonam ELHENCEMahaveer Singh RODHABinit SUREKAEosinophilic solid and cystic renal cell carcinoma (ESC RCC) is a novel tumour with unique morphological and immunohistochemical features. It is a recently described entity after the 2016 World Health Organization Classification of Tumours of the Urinary System and Male Genital Organs and is characterised by a solid cystic tumour composed of polygonal cells with voluminous eosinophilic cytoplasm and CK20 positivity. This tumour has uncertain malignant potential and also has an association with tuberous sclerosis complex (TSC). Sarcomatoid differentiation has not been reported in ESC RCC till now. ESC RCC poses a diagnostic challenge as many eosinophilic/oncocytic renal tumours are included in the differentials. We present a case of ESC RCC with sarcomatoid differentiation in an elderly female without any clinical features of TSC and discuss the differential diagnosis of oncocytic renal tumours. http://www.turkjpath.org/pdf.php3?id=1968 eosinophilic solid and cystic renal cell carcinomaunclassified renal cell carcinomaemerging entityoncocytic renal tumour
spellingShingle Rashim SHARMA
Balamurugan THIRUNAVUKKARASU
Poonam ELHENCE
Mahaveer Singh RODHA
Binit SUREKA
Eosinophilic Solid and Cystic Renal Cell Carcinoma: From Unclassified to Classified, A Case Report
Türk Patoloji Dergisi
eosinophilic solid and cystic renal cell carcinoma
unclassified renal cell carcinoma
emerging entity
oncocytic renal tumour
title Eosinophilic Solid and Cystic Renal Cell Carcinoma: From Unclassified to Classified, A Case Report
title_full Eosinophilic Solid and Cystic Renal Cell Carcinoma: From Unclassified to Classified, A Case Report
title_fullStr Eosinophilic Solid and Cystic Renal Cell Carcinoma: From Unclassified to Classified, A Case Report
title_full_unstemmed Eosinophilic Solid and Cystic Renal Cell Carcinoma: From Unclassified to Classified, A Case Report
title_short Eosinophilic Solid and Cystic Renal Cell Carcinoma: From Unclassified to Classified, A Case Report
title_sort eosinophilic solid and cystic renal cell carcinoma from unclassified to classified a case report
topic eosinophilic solid and cystic renal cell carcinoma
unclassified renal cell carcinoma
emerging entity
oncocytic renal tumour
url http://www.turkjpath.org/pdf.php3?id=1968
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AT poonamelhence eosinophilicsolidandcysticrenalcellcarcinomafromunclassifiedtoclassifiedacasereport
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