The Vicious Cycle of Renal Lipotoxicity and Mitochondrial Dysfunction

The Vicious Cycle of Renal Lipotoxicity and Mitochondrial Dysfunction

The kidney is one of the most energy-demanding organs that require abundant and healthy mitochondria to maintain proper function. Increasing evidence suggests a strong association between mitochondrial dysfunction and chronic kidney diseases (CKDs). Lipids are not only important sources of energy bu...

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Bibliographic Details
Main Authors: Mengyuan Ge, Flavia Fontanesi, Sandra Merscher, Alessia Fornoni
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Physiology
Subjects:
kidney
glomerular diseases
lipotoxicity
mitochondrial dysfunction
oxidative stress
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00732/full

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