Anatomical characterization of central, apical and minimal corneal thickness

<b>AIM:</b> To anatomically locate the points of minimum corneal thickness and central corneal thickness (pupil center) in relation to the corneal apex.<b>METHODS:</b> Observational, cross-sectional study, 299 healthy volunteers. Thickness at the corneal apex (AT), minimum co...

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Main Authors: Federico Saenz-Frances, Martha Cecilia Bermúdez-Vallecilla, Lara Borrego-Sanz, Luis Jañez, José María Martinez-de-la-Casa, Laura Morales-Fernandez, Enrique Santos-Bueso, Julián Garcia-Sanchez, Julián Garcia-Feijoo
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2014-08-01
Series:International Journal of Ophthalmology
Subjects:
Online Access:http://www.ijo.cn/en_publish/2014/4/20140415.pdf
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author Federico Saenz-Frances
Martha Cecilia Bermúdez-Vallecilla
Lara Borrego-Sanz
Luis Jañez
José María Martinez-de-la-Casa
Laura Morales-Fernandez
Enrique Santos-Bueso
Julián Garcia-Sanchez
Julián Garcia-Feijoo
author_facet Federico Saenz-Frances
Martha Cecilia Bermúdez-Vallecilla
Lara Borrego-Sanz
Luis Jañez
José María Martinez-de-la-Casa
Laura Morales-Fernandez
Enrique Santos-Bueso
Julián Garcia-Sanchez
Julián Garcia-Feijoo
author_sort Federico Saenz-Frances
collection DOAJ
description <b>AIM:</b> To anatomically locate the points of minimum corneal thickness and central corneal thickness (pupil center) in relation to the corneal apex.<b>METHODS:</b> Observational, cross-sectional study, 299 healthy volunteers. Thickness at the corneal apex (AT), minimum corneal thickness (MT) and corneal thickness at the pupil center (PT) were determined using the pentacam. Distances from the corneal apex to MT (MD) and PT (PD) were calculated and their quadrant position (taking the corneal apex as the reference) determined:point of minimum thickness (MC) and point of central thickness (PC) depending on the quadrant position. Two multivariate linear regression models were constructed to examine the influence of age, gender, power of the flattest and steepest corneal axes, position of the flattest axis, corneal volume (determined using the Pentacam) and PT on MD and PD. The effects of these variables on MC and PC were also determined in two multinomial regression models.<b>RESULTS:</b> MT was located at a mean distance of 0.909 mm from the apex (79.4% in the inferior-temporal quadrant). PT was located at a mean distance of 0.156 mm from the apex. The linear regression model for MD indicated it was significantly influenced by corneal volume (B=-0.024; 95%CI:-0.043 to -0.004). No significant relations were identified in the linear regression model for PD or the multinomial logistic regressions for MC and PC.<b>CONCLUSION:</b> MT was typically located at the inferior-temporal quadrant of the cornea and its distance to the corneal apex tended to decrease with the increment of corneal volume.
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spelling doaj.art-3aa6bd785f1b43b0ae0d0eb7f43bb3e72022-12-22T00:20:34ZengPress of International Journal of Ophthalmology (IJO PRESS)International Journal of Ophthalmology2222-39592227-48982014-08-017466867210.3980/j.issn.2222-3959.2014.04.15Anatomical characterization of central, apical and minimal corneal thicknessFederico Saenz-Frances0Martha Cecilia Bermúdez-Vallecilla1Lara Borrego-Sanz2Luis Jañez3José María Martinez-de-la-Casa 4Laura Morales-Fernandez5Enrique Santos-Bueso6Julián Garcia-Sanchez7Julián Garcia-Feijoo8Department of Ophthalmology, Hospital Clínico San Carlos, Universidad Complutense de Madrid, Madrid 28040, Spain<br>Department of Ophthalmology, Hospital Clínico San Carlos, Universidad Complutense de Madrid, Madrid 28040, Spain<br>Department of Ophthalmology, Hospital Clínico San Carlos, Universidad Complutense de Madrid, Madrid 28040, Spain<br>Instituto de Tecnología del Conocimiento, Universidad Complutense de Madrid, Madrid 28040, SpainDepartment of Ophthalmology, Hospital Clínico San Carlos, Universidad Complutense de Madrid, Madrid 28040, Spain<br>Department of Ophthalmology, Hospital Clínico San Carlos, Universidad Complutense de Madrid, Madrid 28040, Spain<br>Department of Ophthalmology, Hospital Clínico San Carlos, Universidad Complutense de Madrid, Madrid 28040, Spain<br>Department of Ophthalmology, Hospital Clínico San Carlos, Universidad Complutense de Madrid, Madrid 28040, Spain<br>Department of Ophthalmology, Hospital Clínico San Carlos, Universidad Complutense de Madrid, Madrid 28040, Spain<br><b>AIM:</b> To anatomically locate the points of minimum corneal thickness and central corneal thickness (pupil center) in relation to the corneal apex.<b>METHODS:</b> Observational, cross-sectional study, 299 healthy volunteers. Thickness at the corneal apex (AT), minimum corneal thickness (MT) and corneal thickness at the pupil center (PT) were determined using the pentacam. Distances from the corneal apex to MT (MD) and PT (PD) were calculated and their quadrant position (taking the corneal apex as the reference) determined:point of minimum thickness (MC) and point of central thickness (PC) depending on the quadrant position. Two multivariate linear regression models were constructed to examine the influence of age, gender, power of the flattest and steepest corneal axes, position of the flattest axis, corneal volume (determined using the Pentacam) and PT on MD and PD. The effects of these variables on MC and PC were also determined in two multinomial regression models.<b>RESULTS:</b> MT was located at a mean distance of 0.909 mm from the apex (79.4% in the inferior-temporal quadrant). PT was located at a mean distance of 0.156 mm from the apex. The linear regression model for MD indicated it was significantly influenced by corneal volume (B=-0.024; 95%CI:-0.043 to -0.004). No significant relations were identified in the linear regression model for PD or the multinomial logistic regressions for MC and PC.<b>CONCLUSION:</b> MT was typically located at the inferior-temporal quadrant of the cornea and its distance to the corneal apex tended to decrease with the increment of corneal volume.http://www.ijo.cn/en_publish/2014/4/20140415.pdfcorneal thicknessanatomyglaucomaglaucoma
spellingShingle Federico Saenz-Frances
Martha Cecilia Bermúdez-Vallecilla
Lara Borrego-Sanz
Luis Jañez
José María Martinez-de-la-Casa
Laura Morales-Fernandez
Enrique Santos-Bueso
Julián Garcia-Sanchez
Julián Garcia-Feijoo
Anatomical characterization of central, apical and minimal corneal thickness
International Journal of Ophthalmology
corneal thickness
anatomy
glaucoma
glaucoma
title Anatomical characterization of central, apical and minimal corneal thickness
title_full Anatomical characterization of central, apical and minimal corneal thickness
title_fullStr Anatomical characterization of central, apical and minimal corneal thickness
title_full_unstemmed Anatomical characterization of central, apical and minimal corneal thickness
title_short Anatomical characterization of central, apical and minimal corneal thickness
title_sort anatomical characterization of central apical and minimal corneal thickness
topic corneal thickness
anatomy
glaucoma
glaucoma
url http://www.ijo.cn/en_publish/2014/4/20140415.pdf
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