Osmium-Based Pyrimidine Contrast Tags for Enhanced Nanopore-Based DNA Base Discrimination.

Nanopores are a promising platform in next generation DNA sequencing. In this platform, an individual DNA strand is threaded into nanopore using an electric field, and enzyme-based ratcheting is used to move the strand through the detector. During this process the residual ion current through the po...

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Bibliografiska uppgifter
Huvudupphovsmän: Robert Y Henley, Ana G Vazquez-Pagan, Michael Johnson, Anastassia Kanavarioti, Meni Wanunu
Materialtyp: Artikel
Språk:English
Publicerad: Public Library of Science (PLoS) 2015-01-01
Serie:PLoS ONE
Länkar:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0142155&type=printable