Immune vulnerability of ovarian cancer stem-like cells due to low CD47 expression is protected by surrounding bulk tumor cells

Immune vulnerability of ovarian cancer stem-like cells due to low CD47 expression is protected by surrounding bulk tumor cells

Recurrence of advanced epithelial ovarian cancer is common despite optimal surgical debulking and initial favorable responses to chemotherapy. Evidences suggest that cancer stem cells (CSCs) have inherent resistance to conventional therapies such as chemotherapy and play a decisive role in cancer re...

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Bibliographic Details
Main Authors: Chih-Long Chang, Chao-Chih Wu, Yun-Ting Hsu, Yi-Chiung Hsu
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:OncoImmunology
Subjects:
cancer stem cell
cd47
tumor microenvironment
ovarian cancer
Online Access:http://dx.doi.org/10.1080/2162402X.2020.1803530

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