Gestations course and outcomes in patients with systemic lupus erythematosus
Objective. To study course features and gestation ourcomes in pts with systemic lupus erythematosus (SLE). To assess gestation influence on SLE course and gestation outcomes for fetus and mother. Material and methods. 27 gestation course and outcomes were followed up in 26 women with SLE admitted to...
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Format: | Article |
Language: | Russian |
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IMA PRESS LLC
2003-08-01
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Series: | Научно-практическая ревматология |
Subjects: | |
Online Access: | https://rsp.mediar-press.net/rsp/article/view/1204 |
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author | S J Volkova G R Fadienko N A Levchenko |
author_facet | S J Volkova G R Fadienko N A Levchenko |
author_sort | S J Volkova |
collection | DOAJ |
description | Objective. To study course features and gestation ourcomes in pts with systemic lupus erythematosus (SLE). To assess gestation influence on SLE course and gestation outcomes for fetus and mother. Material and methods. 27 gestation course and outcomes were followed up in 26 women with SLE admitted to Tyumen regional clinical hospital in 1995-2001 years. SLE was diagnosed according to ACR 1982 criteria. Statistical analysis was performed with MS Excel 7.0. Results. SLE exacerbated during gestation in all examined women. Autoimmune process activity increased in most pts after the end of gestation independently on its outcome and required intensive treatment methods administration. Negative perinatal SLE influence on fetus was noted even at favorite prognosis for mother. Programs of immunosuppressive therapy are administered in SLE during gestation. Conclusion. SLE presence worsens gestation course and outcomes determining high percent of medical and spontaneous abortions, exerts negative perinatal influence on fetus. Gestation appearance in pts with SLE as a rule lead to disease exacerbation as during gestation as after delivery. Presented intensive therapy programs allow to ameliorate gestation outcomes for mother and for fetus in SLE. |
first_indexed | 2024-04-09T22:29:18Z |
format | Article |
id | doaj.art-3aaec27ef9c94b8bad87b0ea27e66be7 |
institution | Directory Open Access Journal |
issn | 1995-4484 1995-4492 |
language | Russian |
last_indexed | 2024-04-09T22:29:18Z |
publishDate | 2003-08-01 |
publisher | IMA PRESS LLC |
record_format | Article |
series | Научно-практическая ревматология |
spelling | doaj.art-3aaec27ef9c94b8bad87b0ea27e66be72023-03-22T13:45:39ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922003-08-01414192210.14412/1995-4484-2003-13261144Gestations course and outcomes in patients with systemic lupus erythematosusS J VolkovaG R FadienkoN A LevchenkoObjective. To study course features and gestation ourcomes in pts with systemic lupus erythematosus (SLE). To assess gestation influence on SLE course and gestation outcomes for fetus and mother. Material and methods. 27 gestation course and outcomes were followed up in 26 women with SLE admitted to Tyumen regional clinical hospital in 1995-2001 years. SLE was diagnosed according to ACR 1982 criteria. Statistical analysis was performed with MS Excel 7.0. Results. SLE exacerbated during gestation in all examined women. Autoimmune process activity increased in most pts after the end of gestation independently on its outcome and required intensive treatment methods administration. Negative perinatal SLE influence on fetus was noted even at favorite prognosis for mother. Programs of immunosuppressive therapy are administered in SLE during gestation. Conclusion. SLE presence worsens gestation course and outcomes determining high percent of medical and spontaneous abortions, exerts negative perinatal influence on fetus. Gestation appearance in pts with SLE as a rule lead to disease exacerbation as during gestation as after delivery. Presented intensive therapy programs allow to ameliorate gestation outcomes for mother and for fetus in SLE.https://rsp.mediar-press.net/rsp/article/view/1204systemic lupus erythematosusgestationfetus losesintensive therapy |
spellingShingle | S J Volkova G R Fadienko N A Levchenko Gestations course and outcomes in patients with systemic lupus erythematosus Научно-практическая ревматология systemic lupus erythematosus gestation fetus loses intensive therapy |
title | Gestations course and outcomes in patients with systemic lupus erythematosus |
title_full | Gestations course and outcomes in patients with systemic lupus erythematosus |
title_fullStr | Gestations course and outcomes in patients with systemic lupus erythematosus |
title_full_unstemmed | Gestations course and outcomes in patients with systemic lupus erythematosus |
title_short | Gestations course and outcomes in patients with systemic lupus erythematosus |
title_sort | gestations course and outcomes in patients with systemic lupus erythematosus |
topic | systemic lupus erythematosus gestation fetus loses intensive therapy |
url | https://rsp.mediar-press.net/rsp/article/view/1204 |
work_keys_str_mv | AT sjvolkova gestationscourseandoutcomesinpatientswithsystemiclupuserythematosus AT grfadienko gestationscourseandoutcomesinpatientswithsystemiclupuserythematosus AT nalevchenko gestationscourseandoutcomesinpatientswithsystemiclupuserythematosus |