Gestations course and outcomes in patients with systemic lupus erythematosus

Objective. To study course features and gestation ourcomes in pts with systemic lupus erythematosus (SLE). To assess gestation influence on SLE course and gestation outcomes for fetus and mother. Material and methods. 27 gestation course and outcomes were followed up in 26 women with SLE admitted to...

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Main Authors: S J Volkova, G R Fadienko, N A Levchenko
Format: Article
Language:Russian
Published: IMA PRESS LLC 2003-08-01
Series:Научно-практическая ревматология
Subjects:
Online Access:https://rsp.mediar-press.net/rsp/article/view/1204
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author S J Volkova
G R Fadienko
N A Levchenko
author_facet S J Volkova
G R Fadienko
N A Levchenko
author_sort S J Volkova
collection DOAJ
description Objective. To study course features and gestation ourcomes in pts with systemic lupus erythematosus (SLE). To assess gestation influence on SLE course and gestation outcomes for fetus and mother. Material and methods. 27 gestation course and outcomes were followed up in 26 women with SLE admitted to Tyumen regional clinical hospital in 1995-2001 years. SLE was diagnosed according to ACR 1982 criteria. Statistical analysis was performed with MS Excel 7.0. Results. SLE exacerbated during gestation in all examined women. Autoimmune process activity increased in most pts after the end of gestation independently on its outcome and required intensive treatment methods administration. Negative perinatal SLE influence on fetus was noted even at favorite prognosis for mother. Programs of immunosuppressive therapy are administered in SLE during gestation. Conclusion. SLE presence worsens gestation course and outcomes determining high percent of medical and spontaneous abortions, exerts negative perinatal influence on fetus. Gestation appearance in pts with SLE as a rule lead to disease exacerbation as during gestation as after delivery. Presented intensive therapy programs allow to ameliorate gestation outcomes for mother and for fetus in SLE.
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spelling doaj.art-3aaec27ef9c94b8bad87b0ea27e66be72023-03-22T13:45:39ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922003-08-01414192210.14412/1995-4484-2003-13261144Gestations course and outcomes in patients with systemic lupus erythematosusS J VolkovaG R FadienkoN A LevchenkoObjective. To study course features and gestation ourcomes in pts with systemic lupus erythematosus (SLE). To assess gestation influence on SLE course and gestation outcomes for fetus and mother. Material and methods. 27 gestation course and outcomes were followed up in 26 women with SLE admitted to Tyumen regional clinical hospital in 1995-2001 years. SLE was diagnosed according to ACR 1982 criteria. Statistical analysis was performed with MS Excel 7.0. Results. SLE exacerbated during gestation in all examined women. Autoimmune process activity increased in most pts after the end of gestation independently on its outcome and required intensive treatment methods administration. Negative perinatal SLE influence on fetus was noted even at favorite prognosis for mother. Programs of immunosuppressive therapy are administered in SLE during gestation. Conclusion. SLE presence worsens gestation course and outcomes determining high percent of medical and spontaneous abortions, exerts negative perinatal influence on fetus. Gestation appearance in pts with SLE as a rule lead to disease exacerbation as during gestation as after delivery. Presented intensive therapy programs allow to ameliorate gestation outcomes for mother and for fetus in SLE.https://rsp.mediar-press.net/rsp/article/view/1204systemic lupus erythematosusgestationfetus losesintensive therapy
spellingShingle S J Volkova
G R Fadienko
N A Levchenko
Gestations course and outcomes in patients with systemic lupus erythematosus
Научно-практическая ревматология
systemic lupus erythematosus
gestation
fetus loses
intensive therapy
title Gestations course and outcomes in patients with systemic lupus erythematosus
title_full Gestations course and outcomes in patients with systemic lupus erythematosus
title_fullStr Gestations course and outcomes in patients with systemic lupus erythematosus
title_full_unstemmed Gestations course and outcomes in patients with systemic lupus erythematosus
title_short Gestations course and outcomes in patients with systemic lupus erythematosus
title_sort gestations course and outcomes in patients with systemic lupus erythematosus
topic systemic lupus erythematosus
gestation
fetus loses
intensive therapy
url https://rsp.mediar-press.net/rsp/article/view/1204
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AT grfadienko gestationscourseandoutcomesinpatientswithsystemiclupuserythematosus
AT nalevchenko gestationscourseandoutcomesinpatientswithsystemiclupuserythematosus