Neopterin Determinations in Tuberculous Bone Infections
In patients with tuberculous chest infections caused by intracellular Mycobacteria elevated serum neopterin levels could be found. In the present study neopterin levels were elevated in 5/6 patients with proven tuberculous bone infections as well. Neopterin determinations in serum were especially he...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
1994-05-01
|
| Series: | Pteridines |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/pteridines.1994.5.2.61 |
| _version_ | 1818584714900930560 |
|---|---|
| author | Peters K. M. Schweitzer K. Zimmermann S. Zilkens K. W. |
| author_facet | Peters K. M. Schweitzer K. Zimmermann S. Zilkens K. W. |
| author_sort | Peters K. M. |
| collection | DOAJ |
| description | In patients with tuberculous chest infections caused by intracellular Mycobacteria elevated serum neopterin levels could be found. In the present study neopterin levels were elevated in 5/6 patients with proven tuberculous bone infections as well. Neopterin determinations in serum were especially helpful for the drug monitoring of these patients. After a sufficient antituberculous therapy initially elevated neopterin levels decreased and remained within normal range. Persistent elevation of neopterin may be a hint for a resistance of the Mycobacteria. |
| first_indexed | 2024-12-16T08:25:34Z |
| format | Article |
| id | doaj.art-3aaf6d658d224a5cb6a586303def5656 |
| institution | Directory Open Access Journal |
| issn | 0933-4807 2195-4720 |
| language | English |
| last_indexed | 2024-12-16T08:25:34Z |
| publishDate | 1994-05-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Pteridines |
| spelling | doaj.art-3aaf6d658d224a5cb6a586303def56562022-12-21T22:38:00ZengDe GruyterPteridines0933-48072195-47201994-05-0152616410.1515/pteridines.1994.5.2.61Neopterin Determinations in Tuberculous Bone InfectionsPeters K. M.0Schweitzer K.1Zimmermann S.2Zilkens K. W.3Clinic of Orthopaedic Surgery, Clinic of Orthopaedic Surgery, Klinikum Ingolstadt, Krumenauer str. 25. D--85049 Ingolstadt, GermanyInstitute of Medical Immunology, RWTH Aachen, Pauwelsstr. 30, 0-52057 Aachen, GermanyClinic of Orthopaedic Surgery, RWTH Aachen, Pauwelsstr. 30, 0-52057 Aachen, GermanyClinic of Orthopaedic Surgery, RWTH Aachen, Pauwelsstr. 30, 0-52057 Aachen, GermanyIn patients with tuberculous chest infections caused by intracellular Mycobacteria elevated serum neopterin levels could be found. In the present study neopterin levels were elevated in 5/6 patients with proven tuberculous bone infections as well. Neopterin determinations in serum were especially helpful for the drug monitoring of these patients. After a sufficient antituberculous therapy initially elevated neopterin levels decreased and remained within normal range. Persistent elevation of neopterin may be a hint for a resistance of the Mycobacteria.https://doi.org/10.1515/pteridines.1994.5.2.61neopterinbone infectionmycobacteriadrug monitoring |
| spellingShingle | Peters K. M. Schweitzer K. Zimmermann S. Zilkens K. W. Neopterin Determinations in Tuberculous Bone Infections Pteridines neopterin bone infection mycobacteria drug monitoring |
| title | Neopterin Determinations in Tuberculous Bone Infections |
| title_full | Neopterin Determinations in Tuberculous Bone Infections |
| title_fullStr | Neopterin Determinations in Tuberculous Bone Infections |
| title_full_unstemmed | Neopterin Determinations in Tuberculous Bone Infections |
| title_short | Neopterin Determinations in Tuberculous Bone Infections |
| title_sort | neopterin determinations in tuberculous bone infections |
| topic | neopterin bone infection mycobacteria drug monitoring |
| url | https://doi.org/10.1515/pteridines.1994.5.2.61 |
| work_keys_str_mv | AT peterskm neopterindeterminationsintuberculousboneinfections AT schweitzerk neopterindeterminationsintuberculousboneinfections AT zimmermanns neopterindeterminationsintuberculousboneinfections AT zilkenskw neopterindeterminationsintuberculousboneinfections |