Ensemble Technique Coupled with Deep Transfer Learning Framework for Automatic Detection of Tuberculosis from Chest X-ray Radiographs

Tuberculosis (TB) is an infectious disease affecting humans’ lungs and is currently ranked the 13th leading cause of death globally. Due to advancements in technology and the availability of medical datasets, automatic analysis and classification of chest X-rays (CXRs) into TB and non-TB can be a re...

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Main Authors: Evans Kotei, Ramkumar Thirunavukarasu
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Healthcare
Subjects:
Online Access:https://www.mdpi.com/2227-9032/10/11/2335
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author Evans Kotei
Ramkumar Thirunavukarasu
author_facet Evans Kotei
Ramkumar Thirunavukarasu
author_sort Evans Kotei
collection DOAJ
description Tuberculosis (TB) is an infectious disease affecting humans’ lungs and is currently ranked the 13th leading cause of death globally. Due to advancements in technology and the availability of medical datasets, automatic analysis and classification of chest X-rays (CXRs) into TB and non-TB can be a reliable alternative for early TB screening. We propose an automatic TB detection system using advanced deep learning (DL) models. A substantial part of a CXR image is dark, with no relevant information for diagnosis and potentially confusing DL models. In this work, the U-Net model extracts the region of interest from CXRs and the segmented images are fed to the DL models for feature extraction. Eight different convolutional neural networks (CNN) models are employed in our experiments, and their classification performance is compared based on three publicly available CXR datasets. The U-Net model achieves segmentation accuracy of 98.58%, intersection over union (IoU) of 93.10, and a Dice coefficient score of 96.50. Our proposed stacked ensemble algorithm performed better by achieving accuracy, sensitivity, and specificity values of 98.38%, 98.89%, and 98.70%, respectively. Experimental results confirm that segmented lung CXR images with ensemble learning produce a better result than un-segmented lung CXR images.
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spelling doaj.art-3ab06affb90149b1936ceca1ea01968a2023-11-24T08:28:57ZengMDPI AGHealthcare2227-90322022-11-011011233510.3390/healthcare10112335Ensemble Technique Coupled with Deep Transfer Learning Framework for Automatic Detection of Tuberculosis from Chest X-ray RadiographsEvans Kotei0Ramkumar Thirunavukarasu1School of Information Technology and Engineering, Vellore Institute of Technology, Vellore 632014, IndiaSchool of Information Technology and Engineering, Vellore Institute of Technology, Vellore 632014, IndiaTuberculosis (TB) is an infectious disease affecting humans’ lungs and is currently ranked the 13th leading cause of death globally. Due to advancements in technology and the availability of medical datasets, automatic analysis and classification of chest X-rays (CXRs) into TB and non-TB can be a reliable alternative for early TB screening. We propose an automatic TB detection system using advanced deep learning (DL) models. A substantial part of a CXR image is dark, with no relevant information for diagnosis and potentially confusing DL models. In this work, the U-Net model extracts the region of interest from CXRs and the segmented images are fed to the DL models for feature extraction. Eight different convolutional neural networks (CNN) models are employed in our experiments, and their classification performance is compared based on three publicly available CXR datasets. The U-Net model achieves segmentation accuracy of 98.58%, intersection over union (IoU) of 93.10, and a Dice coefficient score of 96.50. Our proposed stacked ensemble algorithm performed better by achieving accuracy, sensitivity, and specificity values of 98.38%, 98.89%, and 98.70%, respectively. Experimental results confirm that segmented lung CXR images with ensemble learning produce a better result than un-segmented lung CXR images.https://www.mdpi.com/2227-9032/10/11/2335tuberculosis detectiondeep learningtransfer learningensemble learninglung segmentationmedical image analysis
spellingShingle Evans Kotei
Ramkumar Thirunavukarasu
Ensemble Technique Coupled with Deep Transfer Learning Framework for Automatic Detection of Tuberculosis from Chest X-ray Radiographs
Healthcare
tuberculosis detection
deep learning
transfer learning
ensemble learning
lung segmentation
medical image analysis
title Ensemble Technique Coupled with Deep Transfer Learning Framework for Automatic Detection of Tuberculosis from Chest X-ray Radiographs
title_full Ensemble Technique Coupled with Deep Transfer Learning Framework for Automatic Detection of Tuberculosis from Chest X-ray Radiographs
title_fullStr Ensemble Technique Coupled with Deep Transfer Learning Framework for Automatic Detection of Tuberculosis from Chest X-ray Radiographs
title_full_unstemmed Ensemble Technique Coupled with Deep Transfer Learning Framework for Automatic Detection of Tuberculosis from Chest X-ray Radiographs
title_short Ensemble Technique Coupled with Deep Transfer Learning Framework for Automatic Detection of Tuberculosis from Chest X-ray Radiographs
title_sort ensemble technique coupled with deep transfer learning framework for automatic detection of tuberculosis from chest x ray radiographs
topic tuberculosis detection
deep learning
transfer learning
ensemble learning
lung segmentation
medical image analysis
url https://www.mdpi.com/2227-9032/10/11/2335
work_keys_str_mv AT evanskotei ensembletechniquecoupledwithdeeptransferlearningframeworkforautomaticdetectionoftuberculosisfromchestxrayradiographs
AT ramkumarthirunavukarasu ensembletechniquecoupledwithdeeptransferlearningframeworkforautomaticdetectionoftuberculosisfromchestxrayradiographs