Development of tetracycline-modified nanoparticles for bone-targeted delivery of anti-tubercular drug

Background: Since the poor response to existing anti-tuberculosis drugs and low drug concentration in local bone tissues, the traditional drug therapy does not result in satisfactory treatment of osteoarticular tuberculosis. Thus, we report a rifapentine release system with imparted bone targeting p...

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Bibliographic Details
Main Authors: Qiuzhen Liang, Pengfei Zhang, Liang Zhang, Haopeng Luan, Xinxia Li, Haibin Xiang, Shuang Jing, Xinghua Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1207520/full