Preparation of self-assembly silica redox nanoparticles to improve drug encapsulation and suppress the adverse effect of doxorubicin

Preparation of self-assembly silica redox nanoparticles to improve drug encapsulation and suppress the adverse effect of doxorubicin

Background and Purpose: The utilization of doxorubicin (DOX) in clinal trials is also challenging owing to its adverse effects, including low oral bioavailability, generation of reactive oxygen species (ROS), cardiotoxicity, and epithelial barrier damage. Recently, scavenging of ROS reduced the cyt...

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Bibliographic Details
Main Authors: Minh-Dat Quoc Tang, Nhu-Thuy Trinh, Dung Vu, Thu-Ha Thi Nguyen, Hung Thanh Dong, Toi Van Vo, Binh Long Vong
Format: Article
Language:English
Published: International Association of Physical Chemists (IAPC) 2023-07-01
Series:ADMET and DMPK
Subjects:
Chemotherapy
reactive oxygen species
ROS scavengers
micelles nanoparticles
nanomedicine
Online Access:https://pub.iapchem.org/ojs/index.php/admet/article/view/1845

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