Large bowel obstruction during pregnancy: the efficacy of dietary fibers

<p> <b>Yu.E. Dobrokhotova, E.I.&nbsp;Borovkova, T.D.&nbsp;Simonyan, D.S.&nbsp;Selimshaeva</b> </p> <p> <b>Pirogov Russian National Research Medical University, Moscow, Russian Federation</b> </p> <p> <i><b>Aim</b>...

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Main Authors: Yu.E. Dobrokhotova, E.I. Borovkova, T.D. Simonyan, D.S. Selimshaeva
Format: Article
Language:Russian
Published: LCC «Medicine-Inform» 2021-02-01
Series:РМЖ. Мать и дитя
Online Access:http://wchjournal.com/upload/iblock/26d/26d9fb4af0cafbc0c20e7dc22b89cdd6.pdf
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author Yu.E. Dobrokhotova
E.I. Borovkova
T.D. Simonyan
D.S. Selimshaeva
author_facet Yu.E. Dobrokhotova
E.I. Borovkova
T.D. Simonyan
D.S. Selimshaeva
author_sort Yu.E. Dobrokhotova
collection DOAJ
description <p> <b>Yu.E. Dobrokhotova, E.I.&nbsp;Borovkova, T.D.&nbsp;Simonyan, D.S.&nbsp;Selimshaeva</b> </p> <p> <b>Pirogov Russian National Research Medical University, Moscow, Russian Federation</b> </p> <p> <i><b>Aim</b>: to evaluate the clinical efficacy of dietary fibers and lactulose in pregnant women with large bowel obstruction.</i> </p> <p> <i><b>Patients and Methods:</b> this prospective study included 60 pregnant women (20–24 weeks of pregnancy) with large bowel obstruction occurred during pregnancy and persisted for at least 3 months. All women were randomized and divided into two groups. Group 1 received soluble fibers and group 2 received group 2 received lactulose. Clinical efficacy of treatment was evaluated using a specialized questionnaire filled at baseline, 48 h, 4 days, and 14 days after starting treatment.</i> </p> <p> <i><b>Results</b>: mean age was 27.1±4.0 years in group 1 and 28.3±5.0 years in group 2. Bowel evacuation less than 3 times a week occurred in 87% and 77%, respectively, the duration of pushing occupied more than 25% of defecation in 70% and 60%, respectively, hard stool occurred in 100%, anal fissures and a feeling of incomplete evacuation were reported in 47% and 57%, respectively. Comfort bowel evacuation 48 h after starting treatment was reported in 63% of women who received dietary fibers and 47% of patients who received lactulose. Normal defecation by day 4 was observed in 80% of women in group 1 and 53% in group 2. Treatment effect was achieved by day 14 in 87% in group 1 and 70% in group 2. The most common complaint was abdominal distension that occurred 3.5 times more common after treatment with lactulose (р&lt;0.05).</i> </p> <p> <i><b>Conclusions</b>: dietary fibers were more effective in terms of achieving the desired outcome and patient satisfaction.</i> </p> <p> <i><b>Keywords</b>: large bowel obstruction, defecation, pregnancy, dietary fibers, OptiFibere, lactulose.</i> </p> <p> <i><b>For citation:</b> Dobrokhotova Yu.E., Borovkova E.I., Simonyan T.D., Selimshaeva D.S. Large bowel obstruction during pregnancy: the efficacy of dietary fibers. Russian Journal of Woman and Child Health. 2021;4(1):36–41. DOI: 10.32364/2618-8430-2021-4-1-36-41.</i> </p>
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spelling doaj.art-3ab92f12d1bd434da758afcc3f25109d2024-02-26T10:13:32ZrusLCC «Medicine-Inform»РМЖ. Мать и дитя2618-84302686-71842021-02-014133327Large bowel obstruction during pregnancy: the efficacy of dietary fibersYu.E. Dobrokhotova0E.I. Borovkova1T.D. Simonyan2D.S. Selimshaeva3Russian Journal of Woman and Child Health, Publisher of «Medicina-Inform» Address for correspondence: Russia, 105064, Moscow, P.O. Box 399Russian Journal of Woman and Child Health, Publisher of «Medicina-Inform» Address for correspondence: Russia, 105064, Moscow, P.O. Box 399Russian Journal of Woman and Child Health, Publisher of «Medicina-Inform» Address for correspondence: Russia, 105064, Moscow, P.O. Box 399Russian Journal of Woman and Child Health, Publisher of «Medicina-Inform» Address for correspondence: Russia, 105064, Moscow, P.O. Box 399<p> <b>Yu.E. Dobrokhotova, E.I.&nbsp;Borovkova, T.D.&nbsp;Simonyan, D.S.&nbsp;Selimshaeva</b> </p> <p> <b>Pirogov Russian National Research Medical University, Moscow, Russian Federation</b> </p> <p> <i><b>Aim</b>: to evaluate the clinical efficacy of dietary fibers and lactulose in pregnant women with large bowel obstruction.</i> </p> <p> <i><b>Patients and Methods:</b> this prospective study included 60 pregnant women (20–24 weeks of pregnancy) with large bowel obstruction occurred during pregnancy and persisted for at least 3 months. All women were randomized and divided into two groups. Group 1 received soluble fibers and group 2 received group 2 received lactulose. Clinical efficacy of treatment was evaluated using a specialized questionnaire filled at baseline, 48 h, 4 days, and 14 days after starting treatment.</i> </p> <p> <i><b>Results</b>: mean age was 27.1±4.0 years in group 1 and 28.3±5.0 years in group 2. Bowel evacuation less than 3 times a week occurred in 87% and 77%, respectively, the duration of pushing occupied more than 25% of defecation in 70% and 60%, respectively, hard stool occurred in 100%, anal fissures and a feeling of incomplete evacuation were reported in 47% and 57%, respectively. Comfort bowel evacuation 48 h after starting treatment was reported in 63% of women who received dietary fibers and 47% of patients who received lactulose. Normal defecation by day 4 was observed in 80% of women in group 1 and 53% in group 2. Treatment effect was achieved by day 14 in 87% in group 1 and 70% in group 2. The most common complaint was abdominal distension that occurred 3.5 times more common after treatment with lactulose (р&lt;0.05).</i> </p> <p> <i><b>Conclusions</b>: dietary fibers were more effective in terms of achieving the desired outcome and patient satisfaction.</i> </p> <p> <i><b>Keywords</b>: large bowel obstruction, defecation, pregnancy, dietary fibers, OptiFibere, lactulose.</i> </p> <p> <i><b>For citation:</b> Dobrokhotova Yu.E., Borovkova E.I., Simonyan T.D., Selimshaeva D.S. Large bowel obstruction during pregnancy: the efficacy of dietary fibers. Russian Journal of Woman and Child Health. 2021;4(1):36–41. DOI: 10.32364/2618-8430-2021-4-1-36-41.</i> </p>http://wchjournal.com/upload/iblock/26d/26d9fb4af0cafbc0c20e7dc22b89cdd6.pdf
spellingShingle Yu.E. Dobrokhotova
E.I. Borovkova
T.D. Simonyan
D.S. Selimshaeva
Large bowel obstruction during pregnancy: the efficacy of dietary fibers
РМЖ. Мать и дитя
title Large bowel obstruction during pregnancy: the efficacy of dietary fibers
title_full Large bowel obstruction during pregnancy: the efficacy of dietary fibers
title_fullStr Large bowel obstruction during pregnancy: the efficacy of dietary fibers
title_full_unstemmed Large bowel obstruction during pregnancy: the efficacy of dietary fibers
title_short Large bowel obstruction during pregnancy: the efficacy of dietary fibers
title_sort large bowel obstruction during pregnancy the efficacy of dietary fibers
url http://wchjournal.com/upload/iblock/26d/26d9fb4af0cafbc0c20e7dc22b89cdd6.pdf
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AT dsselimshaeva largebowelobstructionduringpregnancytheefficacyofdietaryfibers