Night shift work was associated with functional outcomes in acute ischemic stroke patients treated with endovascular thrombectomy
Objective: This study aimed to explore the impact of late night shift work on the functional outcomes of patients with acute ischemic stroke (AIS) treated with endovascular thrombectomy (EVT). Methods: Consecutive AIS patients who underwent EVT between June 2019 and June 2021 were enrolled and divid...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-02-01
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| Series: | Heliyon |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844024019479 |
| _version_ | 1827322224351117312 |
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| author | Wantong Yu Jin Ma Wenting Guo Jiali Xu Jun Xu Sijie Li Changhong Ren Longfei Wu Chuanjie Wu Chuanhui Li Jian Chen Jiangang Duan Qingfeng Ma Haiqing Song Wenbo Zhao Xunming Ji |
| author_facet | Wantong Yu Jin Ma Wenting Guo Jiali Xu Jun Xu Sijie Li Changhong Ren Longfei Wu Chuanjie Wu Chuanhui Li Jian Chen Jiangang Duan Qingfeng Ma Haiqing Song Wenbo Zhao Xunming Ji |
| author_sort | Wantong Yu |
| collection | DOAJ |
| description | Objective: This study aimed to explore the impact of late night shift work on the functional outcomes of patients with acute ischemic stroke (AIS) treated with endovascular thrombectomy (EVT). Methods: Consecutive AIS patients who underwent EVT between June 2019 and June 2021 were enrolled and divided into non-night shift work and night shift work groups based on their occupational histories. The primary outcome was the modified Rankin Scale score defined 3-month functional outcome. The secondary outcomes were 3-month mortality, symptomatic intracerebral hemorrhage (sICH), ICH and early recanalization. Results: A total of 285 patients were enrolled, 35 patients (12.3%) were night shift workers, who were younger (P < 0.001) and had a significantly higher prevalence of smoking (P < 0.001), hyperlipidemia (P = 0.002), coronary heart disease (P = 0.031), and atrial fibrillation (P < 0.001). The 3-month favorable outcomes were achieved in 44.8% and 25.7% of patients in the non-night shift work and night shift work groups, respectively (adjusted odds ratio [OR]: 0.24, 95% CI: 0.10–0.57; adjusted P = 0.001). No difference was found in 3-month mortality (adjusted OR: 0.43; 95% CI: 0.14–1.25, adjusted P = 0.121), rates of ICH (adjusted OR: 0.73; 95% CI: 0.33–1.60; adjusted P = 0.430), sICH (adjusted OR: 0.75; 95% CI: 0.34–1.67; adjusted P = 0.487), or early successful recanalization (adjusted OR: 0.42; 95% CI: 0.12–1.56; adjusted P = 0.197). These results were consistent after PSM analysis. Conclusion: Our findings suggest that late night shift work is significantly associated with unfavorable outcomes in patients with AIS after EVT. |
| first_indexed | 2024-03-08T00:08:55Z |
| format | Article |
| id | doaj.art-3abc4cd4f3c3427e8dbb42d84c7fd032 |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-04-25T01:21:10Z |
| publishDate | 2024-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-3abc4cd4f3c3427e8dbb42d84c7fd0322024-03-09T09:26:33ZengElsevierHeliyon2405-84402024-02-01104e25916Night shift work was associated with functional outcomes in acute ischemic stroke patients treated with endovascular thrombectomyWantong Yu0Jin Ma1Wenting Guo2Jiali Xu3Jun Xu4Sijie Li5Changhong Ren6Longfei Wu7Chuanjie Wu8Chuanhui Li9Jian Chen10Jiangang Duan11Qingfeng Ma12Haiqing Song13Wenbo Zhao14Xunming Ji15Department of Neurology, Xuanwu Hospital, Capital Medical University Beijing, China; Beijing Key Laboratory of Hypoxia Translational Medicine, Xuanwu Hospital, Capital Medical University Beijing, ChinaDepartment of Neurology, Xuanwu Hospital, Capital Medical University Beijing, ChinaDepartment of Neurology, Xuanwu Hospital, Capital Medical University Beijing, ChinaDepartment of Neurology, Xuanwu Hospital, Capital Medical University Beijing, ChinaBeijing Key Laboratory of Hypoxia Translational Medicine, Xuanwu Hospital, Capital Medical University Beijing, ChinaBeijing Key Laboratory of Hypoxia Translational Medicine, Xuanwu Hospital, Capital Medical University Beijing, China; Department of Emergency, Xuanwu Hospital, Capital Medical University, Beijing, ChinaBeijing Key Laboratory of Hypoxia Translational Medicine, Xuanwu Hospital, Capital Medical University Beijing, ChinaDepartment of Neurology, Xuanwu Hospital, Capital Medical University Beijing, ChinaDepartment of Neurology, Xuanwu Hospital, Capital Medical University Beijing, ChinaBeijing Key Laboratory of Hypoxia Translational Medicine, Xuanwu Hospital, Capital Medical University Beijing, ChinaDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, ChinaDepartment of Emergency, Xuanwu Hospital, Capital Medical University, Beijing, ChinaDepartment of Neurology, Xuanwu Hospital, Capital Medical University Beijing, ChinaDepartment of Neurology, Xuanwu Hospital, Capital Medical University Beijing, ChinaDepartment of Neurology, Xuanwu Hospital, Capital Medical University Beijing, China; Beijing Key Laboratory of Hypoxia Translational Medicine, Xuanwu Hospital, Capital Medical University Beijing, China; Corresponding author. Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China.Department of Neurology, Xuanwu Hospital, Capital Medical University Beijing, China; Beijing Key Laboratory of Hypoxia Translational Medicine, Xuanwu Hospital, Capital Medical University Beijing, China; Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China; Center of Stroke, Beijing Institute for Brain Disorder, Capital Medical University, Beijing, China; Corresponding author. Center of Stroke, Beijing Institute for Brain Disorder, Capital Medical University, Beijing, 100069, China.Objective: This study aimed to explore the impact of late night shift work on the functional outcomes of patients with acute ischemic stroke (AIS) treated with endovascular thrombectomy (EVT). Methods: Consecutive AIS patients who underwent EVT between June 2019 and June 2021 were enrolled and divided into non-night shift work and night shift work groups based on their occupational histories. The primary outcome was the modified Rankin Scale score defined 3-month functional outcome. The secondary outcomes were 3-month mortality, symptomatic intracerebral hemorrhage (sICH), ICH and early recanalization. Results: A total of 285 patients were enrolled, 35 patients (12.3%) were night shift workers, who were younger (P < 0.001) and had a significantly higher prevalence of smoking (P < 0.001), hyperlipidemia (P = 0.002), coronary heart disease (P = 0.031), and atrial fibrillation (P < 0.001). The 3-month favorable outcomes were achieved in 44.8% and 25.7% of patients in the non-night shift work and night shift work groups, respectively (adjusted odds ratio [OR]: 0.24, 95% CI: 0.10–0.57; adjusted P = 0.001). No difference was found in 3-month mortality (adjusted OR: 0.43; 95% CI: 0.14–1.25, adjusted P = 0.121), rates of ICH (adjusted OR: 0.73; 95% CI: 0.33–1.60; adjusted P = 0.430), sICH (adjusted OR: 0.75; 95% CI: 0.34–1.67; adjusted P = 0.487), or early successful recanalization (adjusted OR: 0.42; 95% CI: 0.12–1.56; adjusted P = 0.197). These results were consistent after PSM analysis. Conclusion: Our findings suggest that late night shift work is significantly associated with unfavorable outcomes in patients with AIS after EVT.http://www.sciencedirect.com/science/article/pii/S2405844024019479Night shift workIschemic strokeEndovascular therapyFunctional outcome |
| spellingShingle | Wantong Yu Jin Ma Wenting Guo Jiali Xu Jun Xu Sijie Li Changhong Ren Longfei Wu Chuanjie Wu Chuanhui Li Jian Chen Jiangang Duan Qingfeng Ma Haiqing Song Wenbo Zhao Xunming Ji Night shift work was associated with functional outcomes in acute ischemic stroke patients treated with endovascular thrombectomy Heliyon Night shift work Ischemic stroke Endovascular therapy Functional outcome |
| title | Night shift work was associated with functional outcomes in acute ischemic stroke patients treated with endovascular thrombectomy |
| title_full | Night shift work was associated with functional outcomes in acute ischemic stroke patients treated with endovascular thrombectomy |
| title_fullStr | Night shift work was associated with functional outcomes in acute ischemic stroke patients treated with endovascular thrombectomy |
| title_full_unstemmed | Night shift work was associated with functional outcomes in acute ischemic stroke patients treated with endovascular thrombectomy |
| title_short | Night shift work was associated with functional outcomes in acute ischemic stroke patients treated with endovascular thrombectomy |
| title_sort | night shift work was associated with functional outcomes in acute ischemic stroke patients treated with endovascular thrombectomy |
| topic | Night shift work Ischemic stroke Endovascular therapy Functional outcome |
| url | http://www.sciencedirect.com/science/article/pii/S2405844024019479 |
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