Preparation, Characterization, and Bioactivity Evaluation of Polyoxymethylene Copolymer/Nanohydroxyapatite-g-Poly(ε-caprolactone) Composites
In this work, nanohydroxyapatite (HAp) was functionalized with poly(ε-caprolactone) (PCL), using 1,6-hexamethylene diisocyanate (HDI) as a coupling agent, and then incorporated into the polyoxymethylene copolymer (POM) matrix using the extrusion technique. The obtained POM/HAp-g-PCL composites were...
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MDPI AG
2022-03-01
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| Series: | Nanomaterials |
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| Online Access: | https://www.mdpi.com/2079-4991/12/5/858 |
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| author | Kinga Pielichowska Paula Szuba Joanna Maciocha Beata Macherzyńska Katarzyna Nowicka Piotr Szatkowski |
| author_facet | Kinga Pielichowska Paula Szuba Joanna Maciocha Beata Macherzyńska Katarzyna Nowicka Piotr Szatkowski |
| author_sort | Kinga Pielichowska |
| collection | DOAJ |
| description | In this work, nanohydroxyapatite (HAp) was functionalized with poly(ε-caprolactone) (PCL), using 1,6-hexamethylene diisocyanate (HDI) as a coupling agent, and then incorporated into the polyoxymethylene copolymer (POM) matrix using the extrusion technique. The obtained POM/HAp-g-PCL composites were investigated using FTIR, DSC, TOPEM DSC, and TG methods. Mechanical properties were studied using destructive and non-destructive ultrasonic methods, wettability, and POM crystallization kinetics in the presence of HAp-g-PCL. Moreover, preliminary bioactivity evaluation of the POM/HAp-g-PCL composites was performed using the Kokubo method. It was found that the introduction of HAp-g-PCL to the POM matrix has a limited effect on the phase transitions of POM as well as on its degree of crystallinity. Importantly, HAp grafted with PCL caused a significant increase in the thermal stability of the POM, from 292 °C for pristine POM to 333 °C for POM modified with 2.5% HAp-g-PCL. If unmodified HAp was used, a distinct decrease in the thermal stability of the POM was observed. Crystallization kinetic studies confirmed that HAp-g-PCL, in small amounts, can act as a nucleating agent for the POM crystallization process. Moreover, incorporation of HAp-g-PCL, although slightly decreasing the mechanical properties of POM composites, improved the crucial parameter in biomedical applications, namely the in vitro bioactivity. |
| first_indexed | 2024-03-09T20:28:02Z |
| format | Article |
| id | doaj.art-3abf7d9cd8214a9ba1bdb8d44dfcc9d5 |
| institution | Directory Open Access Journal |
| issn | 2079-4991 |
| language | English |
| last_indexed | 2024-03-09T20:28:02Z |
| publishDate | 2022-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj.art-3abf7d9cd8214a9ba1bdb8d44dfcc9d52023-11-23T23:31:15ZengMDPI AGNanomaterials2079-49912022-03-0112585810.3390/nano12050858Preparation, Characterization, and Bioactivity Evaluation of Polyoxymethylene Copolymer/Nanohydroxyapatite-g-Poly(ε-caprolactone) CompositesKinga Pielichowska0Paula Szuba1Joanna Maciocha2Beata Macherzyńska3Katarzyna Nowicka4Piotr Szatkowski5Department of Biomaterials and Composites, Faculty of Materials Science and Ceramics, AGH University of Science and Technology, Al. Mickiewicza 30, 30-059 Kraków, PolandDepartment of Biomaterials and Composites, Faculty of Materials Science and Ceramics, AGH University of Science and Technology, Al. Mickiewicza 30, 30-059 Kraków, PolandDepartment of Biomaterials and Composites, Faculty of Materials Science and Ceramics, AGH University of Science and Technology, Al. Mickiewicza 30, 30-059 Kraków, PolandDepartment of Biomaterials and Composites, Faculty of Materials Science and Ceramics, AGH University of Science and Technology, Al. Mickiewicza 30, 30-059 Kraków, PolandDepartment of Biomaterials and Composites, Faculty of Materials Science and Ceramics, AGH University of Science and Technology, Al. Mickiewicza 30, 30-059 Kraków, PolandDepartment of Biomaterials and Composites, Faculty of Materials Science and Ceramics, AGH University of Science and Technology, Al. Mickiewicza 30, 30-059 Kraków, PolandIn this work, nanohydroxyapatite (HAp) was functionalized with poly(ε-caprolactone) (PCL), using 1,6-hexamethylene diisocyanate (HDI) as a coupling agent, and then incorporated into the polyoxymethylene copolymer (POM) matrix using the extrusion technique. The obtained POM/HAp-g-PCL composites were investigated using FTIR, DSC, TOPEM DSC, and TG methods. Mechanical properties were studied using destructive and non-destructive ultrasonic methods, wettability, and POM crystallization kinetics in the presence of HAp-g-PCL. Moreover, preliminary bioactivity evaluation of the POM/HAp-g-PCL composites was performed using the Kokubo method. It was found that the introduction of HAp-g-PCL to the POM matrix has a limited effect on the phase transitions of POM as well as on its degree of crystallinity. Importantly, HAp grafted with PCL caused a significant increase in the thermal stability of the POM, from 292 °C for pristine POM to 333 °C for POM modified with 2.5% HAp-g-PCL. If unmodified HAp was used, a distinct decrease in the thermal stability of the POM was observed. Crystallization kinetic studies confirmed that HAp-g-PCL, in small amounts, can act as a nucleating agent for the POM crystallization process. Moreover, incorporation of HAp-g-PCL, although slightly decreasing the mechanical properties of POM composites, improved the crucial parameter in biomedical applications, namely the in vitro bioactivity.https://www.mdpi.com/2079-4991/12/5/858polyoxymethylenefunctionalizationnanohydroxyapatitethermal propertiesmechanical properties |
| spellingShingle | Kinga Pielichowska Paula Szuba Joanna Maciocha Beata Macherzyńska Katarzyna Nowicka Piotr Szatkowski Preparation, Characterization, and Bioactivity Evaluation of Polyoxymethylene Copolymer/Nanohydroxyapatite-g-Poly(ε-caprolactone) Composites Nanomaterials polyoxymethylene functionalization nanohydroxyapatite thermal properties mechanical properties |
| title | Preparation, Characterization, and Bioactivity Evaluation of Polyoxymethylene Copolymer/Nanohydroxyapatite-g-Poly(ε-caprolactone) Composites |
| title_full | Preparation, Characterization, and Bioactivity Evaluation of Polyoxymethylene Copolymer/Nanohydroxyapatite-g-Poly(ε-caprolactone) Composites |
| title_fullStr | Preparation, Characterization, and Bioactivity Evaluation of Polyoxymethylene Copolymer/Nanohydroxyapatite-g-Poly(ε-caprolactone) Composites |
| title_full_unstemmed | Preparation, Characterization, and Bioactivity Evaluation of Polyoxymethylene Copolymer/Nanohydroxyapatite-g-Poly(ε-caprolactone) Composites |
| title_short | Preparation, Characterization, and Bioactivity Evaluation of Polyoxymethylene Copolymer/Nanohydroxyapatite-g-Poly(ε-caprolactone) Composites |
| title_sort | preparation characterization and bioactivity evaluation of polyoxymethylene copolymer nanohydroxyapatite g poly ε caprolactone composites |
| topic | polyoxymethylene functionalization nanohydroxyapatite thermal properties mechanical properties |
| url | https://www.mdpi.com/2079-4991/12/5/858 |
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