Astrocytes exhibit diverse Ca2+ changes at subcellular domains during brain aging

Astrocytes exhibit diverse Ca2+ changes at subcellular domains during brain aging

Astrocytic Ca2+ transients are essential for astrocyte integration into neural circuits. These Ca2+ transients are primarily sequestered in subcellular domains, including primary branches, branchlets and leaflets, and endfeet. In previous studies, it suggests that aging causes functional defects in...

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Bibliographic Details
Main Authors: Fusheng Ding, Shanshan Liang, Ruijie Li, Zhiqi Yang, Yong He, Shaofan Yang, Qingtian Duan, Jianxiong Zhang, Jing Lyu, Zhenqiao Zhou, Mingzhu Huang, Haoyu Wang, Jin Li, Chuanyan Yang, Yuxia Wang, Mingyue Gong, Shangbin Chen, Hongbo Jia, Xiaowei Chen, Xiang Liao, Ling Fu, Kuan Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Aging Neuroscience
Subjects:
astrocyte
Ca2+ transients
branches
branchlets and leaflets
endfeet
aging
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2022.1029533/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2022.1029533/full

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