A Drosophila Reporter for the Translational Activation of ATF4 Marks Stressed Cells during Development.

A Drosophila Reporter for the Translational Activation of ATF4 Marks Stressed Cells during Development.

Eukaryotic cells have evolved signaling pathways that help to restore cellular homeostasis in response to various physiological or pathological conditions. ATF4 is a transcription factor whose mRNA translation is stimulated in response to stress-activated eIF2alpha kinases. Established conditions th...

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Bibliographic Details
Main Authors: Kwonyoon Kang, Hyung Don Ryoo, Jung-Eun Park, Jee-Hyun Yoon, Min-Ji Kang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4433282?pdf=render

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