Histopathological Study of Lower Gastrointestinal Tract Biopsies in 600 Cases
Introduction: Broadly the whole gastrointestinal tract can be divided into upper and lower segments by taking the insertion of ligament of Treitz as a landmark. The disorders of Lower Gastrointestinal Tract (LGIT) are responsible for a great number of morbidity. The microscopic analysis and the...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2021-03-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://www.jcdr.net/articles/PDF/14756/47391_CE[Ra1]_F[SK]_PF1(AG_KM)_PFA(SL)_PB(AG_KM)_PN(KM).pdf |
| Summary: | Introduction: Broadly the whole gastrointestinal tract can
be divided into upper and lower segments by taking the
insertion of ligament of Treitz as a landmark. The disorders
of Lower Gastrointestinal Tract (LGIT) are responsible for a
great number of morbidity. The microscopic analysis and
the determination of histological types are thus helpful
in deciding treatment options, predicting prognosis and
conducting epidemiological studies and research. Delay in
diagnosis causes direct as well as distant metastasis leading
to advanced stage of the disease.
Aim: To emphasise the usefulness of LGIT biopsy in diagnosing
the conditions, thus helping the surgeons to decide further
management prior to resection, especially in malignant cases.
Materials and Methods: An observational retrospective study
of various LGIT biopsies was done at Pathology Department
of Sumandeep Vidyapeeth, Vadodara, Gujarat, India. The study
was based on the HPE of lesions received in the duration from
June 2019 to September 2020. In this study, the records of LGIT
specimens including small intestine, large intestine, rectum and
anus were included. Due importance was paid to brief clinical
history with patient’s age, inpatient number and presenting
signs and symptoms. A total of 600 specimens were analysed.
Results: Non-neoplastic lesions were more common than
neoplastic lesions (570 out of 600). Lesions were more common
in 2nd to 5th decades with male preponderance. Among nonneoplastic lesions, majority of non-neoplastic lesion were of
appendiceal lesion (247) followed by non-specific inflammation
(138). Out of 30 neoplastic lesions; most common were of
adenocarcinoma (15 cases).
Conclusion: A wide variety of neoplastic and non-neoplastic
lesions were diagnosed in the present study. In small intestine,
non-neoplastic lesions were common while most of the
malignant lesions were common in large intestine. The most
common non-neoplastic lesion was appendicitis followed by
non-specific inflammation and the most common neoplastic
lesion was adenocarcinoma. |
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| ISSN: | 2249-782X 0973-709X |