The orbital and sinonasal hemangiopericytoma, 2 case reports:

Background & objective: Hemangiopericytoma is an uncommon vascular tumor derived from the pericytes of Zimmermann. . The most common location of the tumor is pelvic retroperitoneum and musculoskeletal system of the lower extremities. It is rarely seen in the head and neck area. In addition, only...

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Main Authors: Maryam Maghbol, Mohammadjavad ashraf, Negar Azarpira
Format: Article
Language:English
Published: Fasa University of Medical Sciences 2015-12-01
Series:Journal of Advanced Biomedical Sciences
Subjects:
Online Access:http://jabs.fums.ac.ir/article-1-758-en.pdf
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author Maryam Maghbol
Mohammadjavad ashraf
Negar Azarpira
author_facet Maryam Maghbol
Mohammadjavad ashraf
Negar Azarpira
author_sort Maryam Maghbol
collection DOAJ
description Background & objective: Hemangiopericytoma is an uncommon vascular tumor derived from the pericytes of Zimmermann. . The most common location of the tumor is pelvic retroperitoneum and musculoskeletal system of the lower extremities. It is rarely seen in the head and neck area. In addition, only 0.8% to 3% of all orbital tumors and less than 5 % of primary sinonasal tumors are primary hemangiopericytoma, which demonstrates that the orbital and sinonasal cavities are rare locations for this tumor. Case: 2 cases of primary orbital and sinonasal hemangiopericytoma that were successfully treated through surgery were reported. Conclusion: Hemangiopericytoma is an uncommon vascular tumor which has a potentially malignant behavior. Histopathologic features alone do not predict the biologic behavior of the tumor but the increased cellularity, necrosis, hemorrhage and more than 4 mitotic figures per 10 high power field, may elicit a diagnosis of malignant hemangiopericytoma . The local recurrence and the distant metastasis might also occur with an incomplete excision.  The lung, bone and liver are the most common sites of distant metastasis. Thus, the long-term follow-up is recommended after the surgical removal of the tumor.
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spelling doaj.art-3ac7e5b70d9b44869d6699cb148b54a82023-09-20T21:21:07ZengFasa University of Medical SciencesJournal of Advanced Biomedical Sciences2228-51052783-15232015-12-0154444448The orbital and sinonasal hemangiopericytoma, 2 case reports:Maryam Maghbol0Mohammadjavad ashraf1Negar Azarpira2 Pathology department of fassa University of Medical Sciences, fassa, Iran. Pathology department of Shiraz University of Medical Sciences, Shiraz, Iran. Transplant research center, Shiraz University of Medical Sciences, Shiraz, Iran. Background & objective: Hemangiopericytoma is an uncommon vascular tumor derived from the pericytes of Zimmermann. . The most common location of the tumor is pelvic retroperitoneum and musculoskeletal system of the lower extremities. It is rarely seen in the head and neck area. In addition, only 0.8% to 3% of all orbital tumors and less than 5 % of primary sinonasal tumors are primary hemangiopericytoma, which demonstrates that the orbital and sinonasal cavities are rare locations for this tumor. Case: 2 cases of primary orbital and sinonasal hemangiopericytoma that were successfully treated through surgery were reported. Conclusion: Hemangiopericytoma is an uncommon vascular tumor which has a potentially malignant behavior. Histopathologic features alone do not predict the biologic behavior of the tumor but the increased cellularity, necrosis, hemorrhage and more than 4 mitotic figures per 10 high power field, may elicit a diagnosis of malignant hemangiopericytoma . The local recurrence and the distant metastasis might also occur with an incomplete excision.  The lung, bone and liver are the most common sites of distant metastasis. Thus, the long-term follow-up is recommended after the surgical removal of the tumor.http://jabs.fums.ac.ir/article-1-758-en.pdforbital and sinonasal hemangiopericytomaproptosisepistaxis
spellingShingle Maryam Maghbol
Mohammadjavad ashraf
Negar Azarpira
The orbital and sinonasal hemangiopericytoma, 2 case reports:
Journal of Advanced Biomedical Sciences
orbital and sinonasal hemangiopericytoma
proptosis
epistaxis
title The orbital and sinonasal hemangiopericytoma, 2 case reports:
title_full The orbital and sinonasal hemangiopericytoma, 2 case reports:
title_fullStr The orbital and sinonasal hemangiopericytoma, 2 case reports:
title_full_unstemmed The orbital and sinonasal hemangiopericytoma, 2 case reports:
title_short The orbital and sinonasal hemangiopericytoma, 2 case reports:
title_sort orbital and sinonasal hemangiopericytoma 2 case reports
topic orbital and sinonasal hemangiopericytoma
proptosis
epistaxis
url http://jabs.fums.ac.ir/article-1-758-en.pdf
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AT mohammadjavadashraf theorbitalandsinonasalhemangiopericytoma2casereports
AT negarazarpira theorbitalandsinonasalhemangiopericytoma2casereports
AT maryammaghbol orbitalandsinonasalhemangiopericytoma2casereports
AT mohammadjavadashraf orbitalandsinonasalhemangiopericytoma2casereports
AT negarazarpira orbitalandsinonasalhemangiopericytoma2casereports