Potentiometric Electronic Tongue for Pharmaceutical Analytics: Determination of Ascorbic Acid Based on Electropolymerized Films

This work deals with the design of an experimental potentiometric electronic tongue (ET) for the recognition of various samples of effervescent tablets with different ascorbic acid (vitamin C) contents. The ET consisted of twelve potentiometric sensors based on conductive polymers, which were derive...

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Main Authors: Gabriela Broncová, Vadim Prokopec, Tatiana V. Shishkanova
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Chemosensors
Subjects:
Online Access:https://www.mdpi.com/2227-9040/9/5/110
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author Gabriela Broncová
Vadim Prokopec
Tatiana V. Shishkanova
author_facet Gabriela Broncová
Vadim Prokopec
Tatiana V. Shishkanova
author_sort Gabriela Broncová
collection DOAJ
description This work deals with the design of an experimental potentiometric electronic tongue (ET) for the recognition of various samples of effervescent tablets with different ascorbic acid (vitamin C) contents. The ET consisted of twelve potentiometric sensors based on conductive polymers, which were derived from 4-amino-2,1,3-benzothiadiazole, 3,4-diaminobenzoic acid, and neutral red on the surface of the platinum electrode using cyclic voltammetry. The aim of the potentiometric study was to assess the influence of the vitamin C content and the composition of the matrix of commercial samples on the potentiometric response. The results obtained from the sensor array proved that the stability of the potentiometric signal and the accuracy of measurements are affected by individual sensors. The identification of the vitamin C content in the individual samples of effervescent tablets obtained by means of the potentiometric electronic tongue corresponded with the results of the coulometric titration.
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spelling doaj.art-3ac9335fe9884c8eb963a517f0f8fad92023-11-21T19:42:49ZengMDPI AGChemosensors2227-90402021-05-019511010.3390/chemosensors9050110Potentiometric Electronic Tongue for Pharmaceutical Analytics: Determination of Ascorbic Acid Based on Electropolymerized FilmsGabriela Broncová0Vadim Prokopec1Tatiana V. Shishkanova2Department of Analytical Chemistry, University of Chemistry and Technology, Technická 5, 166 28 Prague, Czech RepublicDepartment of Analytical Chemistry, University of Chemistry and Technology, Technická 5, 166 28 Prague, Czech RepublicDepartment of Analytical Chemistry, University of Chemistry and Technology, Technická 5, 166 28 Prague, Czech RepublicThis work deals with the design of an experimental potentiometric electronic tongue (ET) for the recognition of various samples of effervescent tablets with different ascorbic acid (vitamin C) contents. The ET consisted of twelve potentiometric sensors based on conductive polymers, which were derived from 4-amino-2,1,3-benzothiadiazole, 3,4-diaminobenzoic acid, and neutral red on the surface of the platinum electrode using cyclic voltammetry. The aim of the potentiometric study was to assess the influence of the vitamin C content and the composition of the matrix of commercial samples on the potentiometric response. The results obtained from the sensor array proved that the stability of the potentiometric signal and the accuracy of measurements are affected by individual sensors. The identification of the vitamin C content in the individual samples of effervescent tablets obtained by means of the potentiometric electronic tongue corresponded with the results of the coulometric titration.https://www.mdpi.com/2227-9040/9/5/110electronic tongueconducting polymerelectropolymerized filmascorbic acideffervescent tabletstability
spellingShingle Gabriela Broncová
Vadim Prokopec
Tatiana V. Shishkanova
Potentiometric Electronic Tongue for Pharmaceutical Analytics: Determination of Ascorbic Acid Based on Electropolymerized Films
Chemosensors
electronic tongue
conducting polymer
electropolymerized film
ascorbic acid
effervescent tablet
stability
title Potentiometric Electronic Tongue for Pharmaceutical Analytics: Determination of Ascorbic Acid Based on Electropolymerized Films
title_full Potentiometric Electronic Tongue for Pharmaceutical Analytics: Determination of Ascorbic Acid Based on Electropolymerized Films
title_fullStr Potentiometric Electronic Tongue for Pharmaceutical Analytics: Determination of Ascorbic Acid Based on Electropolymerized Films
title_full_unstemmed Potentiometric Electronic Tongue for Pharmaceutical Analytics: Determination of Ascorbic Acid Based on Electropolymerized Films
title_short Potentiometric Electronic Tongue for Pharmaceutical Analytics: Determination of Ascorbic Acid Based on Electropolymerized Films
title_sort potentiometric electronic tongue for pharmaceutical analytics determination of ascorbic acid based on electropolymerized films
topic electronic tongue
conducting polymer
electropolymerized film
ascorbic acid
effervescent tablet
stability
url https://www.mdpi.com/2227-9040/9/5/110
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AT vadimprokopec potentiometricelectronictongueforpharmaceuticalanalyticsdeterminationofascorbicacidbasedonelectropolymerizedfilms
AT tatianavshishkanova potentiometricelectronictongueforpharmaceuticalanalyticsdeterminationofascorbicacidbasedonelectropolymerizedfilms