Methodological variation in economic evaluations conducted in low- and middle-income countries: information for reference case development.

Information generated from economic evaluation is increasingly being used to inform health resource allocation decisions globally, including in low- and middle- income countries. However, a crucial consideration for users of the information at a policy level, e.g. funding agencies, is whether the st...

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Main Authors: Benjarin Santatiwongchai, Varit Chantarastapornchit, Thomas Wilkinson, Kittiphong Thiboonboon, Waranya Rattanavipapong, Damian G Walker, Kalipso Chalkidou, Yot Teerawattananon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0123853
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author Benjarin Santatiwongchai
Varit Chantarastapornchit
Thomas Wilkinson
Kittiphong Thiboonboon
Waranya Rattanavipapong
Damian G Walker
Kalipso Chalkidou
Yot Teerawattananon
author_facet Benjarin Santatiwongchai
Varit Chantarastapornchit
Thomas Wilkinson
Kittiphong Thiboonboon
Waranya Rattanavipapong
Damian G Walker
Kalipso Chalkidou
Yot Teerawattananon
author_sort Benjarin Santatiwongchai
collection DOAJ
description Information generated from economic evaluation is increasingly being used to inform health resource allocation decisions globally, including in low- and middle- income countries. However, a crucial consideration for users of the information at a policy level, e.g. funding agencies, is whether the studies are comparable, provide sufficient detail to inform policy decision making, and incorporate inputs from data sources that are reliable and relevant to the context. This review was conducted to inform a methodological standardisation workstream at the Bill and Melinda Gates Foundation (BMGF) and assesses BMGF-funded cost-per-DALY economic evaluations in four programme areas (malaria, tuberculosis, HIV/AIDS and vaccines) in terms of variation in methodology, use of evidence, and quality of reporting. The findings suggest that there is room for improvement in the three areas of assessment, and support the case for the introduction of a standardised methodology or reference case by the BMGF. The findings are also instructive for all institutions that fund economic evaluations in LMICs and who have a desire to improve the ability of economic evaluations to inform resource allocation decisions.
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spelling doaj.art-3acb5ce23a8d4efd99eeb0f4da0ea59c2022-12-21T19:54:07ZengPublic Library of Science (PLoS)PLoS ONE1932-62032015-01-01105e012385310.1371/journal.pone.0123853Methodological variation in economic evaluations conducted in low- and middle-income countries: information for reference case development.Benjarin SantatiwongchaiVarit ChantarastapornchitThomas WilkinsonKittiphong ThiboonboonWaranya RattanavipapongDamian G WalkerKalipso ChalkidouYot TeerawattananonInformation generated from economic evaluation is increasingly being used to inform health resource allocation decisions globally, including in low- and middle- income countries. However, a crucial consideration for users of the information at a policy level, e.g. funding agencies, is whether the studies are comparable, provide sufficient detail to inform policy decision making, and incorporate inputs from data sources that are reliable and relevant to the context. This review was conducted to inform a methodological standardisation workstream at the Bill and Melinda Gates Foundation (BMGF) and assesses BMGF-funded cost-per-DALY economic evaluations in four programme areas (malaria, tuberculosis, HIV/AIDS and vaccines) in terms of variation in methodology, use of evidence, and quality of reporting. The findings suggest that there is room for improvement in the three areas of assessment, and support the case for the introduction of a standardised methodology or reference case by the BMGF. The findings are also instructive for all institutions that fund economic evaluations in LMICs and who have a desire to improve the ability of economic evaluations to inform resource allocation decisions.https://doi.org/10.1371/journal.pone.0123853
spellingShingle Benjarin Santatiwongchai
Varit Chantarastapornchit
Thomas Wilkinson
Kittiphong Thiboonboon
Waranya Rattanavipapong
Damian G Walker
Kalipso Chalkidou
Yot Teerawattananon
Methodological variation in economic evaluations conducted in low- and middle-income countries: information for reference case development.
PLoS ONE
title Methodological variation in economic evaluations conducted in low- and middle-income countries: information for reference case development.
title_full Methodological variation in economic evaluations conducted in low- and middle-income countries: information for reference case development.
title_fullStr Methodological variation in economic evaluations conducted in low- and middle-income countries: information for reference case development.
title_full_unstemmed Methodological variation in economic evaluations conducted in low- and middle-income countries: information for reference case development.
title_short Methodological variation in economic evaluations conducted in low- and middle-income countries: information for reference case development.
title_sort methodological variation in economic evaluations conducted in low and middle income countries information for reference case development
url https://doi.org/10.1371/journal.pone.0123853
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