Exploring microbial diversity and taxonomy using SSU rRNA hypervariable tag sequencing.

Exploring microbial diversity and taxonomy using SSU rRNA hypervariable tag sequencing.

Massively parallel pyrosequencing of hypervariable regions from small subunit ribosomal RNA (SSU rRNA) genes can sample a microbial community two or three orders of magnitude more deeply per dollar and per hour than capillary sequencing of full-length SSU rRNA. As with full-length rRNA surveys, each...

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Bibliographic Details
Main Authors: Susan M Huse, Les Dethlefsen, Julie A Huber, David Mark Welch, David A Relman, Mitchell L Sogin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-11-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2577301?pdf=render

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