New interventional neuroradiological procedures in Serbia: The direct costs of classical neurosurgical intervention in relation to the endovascular treatment of intracranial aneurysms

Introduction: Intracranial aneurysms are one of the major causes of the neurosurgical morbidity and mortality. Each new therapeutic method, in relation to the standard one, generates high medical costs, as a rule. There have not been estimate of costs of treatment of intracranial aneurysms in Serbia...

Full description

Bibliographic Details
Main Authors: Majstorović Branislava M., Milošević-Medenica Svetlana B., Milaković Branko D., Naumović Tamara S.
Format: Article
Language:English
Published: Srpsko lekarsko drustvo 2015-01-01
Series:Hospital Pharmacology
Subjects:
Online Access:http://scindeks-clanci.ceon.rs/data/pdf/2334-9492/2015/2334-94921502272M.pdf
_version_ 1819064222517035008
author Majstorović Branislava M.
Milošević-Medenica Svetlana B.
Milaković Branko D.
Naumović Tamara S.
author_facet Majstorović Branislava M.
Milošević-Medenica Svetlana B.
Milaković Branko D.
Naumović Tamara S.
author_sort Majstorović Branislava M.
collection DOAJ
description Introduction: Intracranial aneurysms are one of the major causes of the neurosurgical morbidity and mortality. Each new therapeutic method, in relation to the standard one, generates high medical costs, as a rule. There have not been estimate of costs of treatment of intracranial aneurysms in Serbia. Objective: The aim of this study was to compare direct medical costs of clipping the neck of the aneurysm in relation to the new neuroradiological technique based on filling the aneurysmal sack with platinum coils and/or stenting the neck of the aneurysm. Methods: In a study approved by the Ethics committee of the Belgrade School of Medicine, we retrospectively measured the direct costs of treatment of bleeding and nonbleeding aneurysms at the Clinic of Neurosurgery, Clinical Centre of Serbia (CCS) in 2010. The study included a total of 300 patients divided in two groups: 1) study group included 99 patients with embolized aneurysms and 2) control group included 201 patients who were operated on by classical neurosurgical technique. Direct medical costs were calculated by the methodology of the State Health Care Insurance Fund. Analysis of results was performed using a software package SPSS. Results: Endovascular treatment was associated with 3% of adverse effects, lower mortality (2% vs. 2.9%), significantly shorter length of hospital stay (Z = - 8.566; p < 0.01), longer duration of anesthesia (226.7 to 195.2 minutes) and significantly higher costs (Z = - 12.475; p < 0.01) compared to neurosurgical treatment. A significant difference in costs was determined mainly by the price of embolization material, 328,169 RSD per patient (3,111€), and the number of resolved aneurysms (more than one, when the multiple aneurysms were treated). Conclusion: The procedural costs of embolization technique are high, as opposed to small number of hospital days. The readiness of the State Health Care Insurance Fund to pay for the costs of embolization should be approved following cost-utility analysis of both modalities, for the longer period of time.
first_indexed 2024-12-21T15:27:08Z
format Article
id doaj.art-3acfe5c5e18944a68d2f8cac7816766b
institution Directory Open Access Journal
issn 2334-9492
2334-9492
language English
last_indexed 2024-12-21T15:27:08Z
publishDate 2015-01-01
publisher Srpsko lekarsko drustvo
record_format Article
series Hospital Pharmacology
spelling doaj.art-3acfe5c5e18944a68d2f8cac7816766b2022-12-21T18:58:53ZengSrpsko lekarsko drustvoHospital Pharmacology2334-94922334-94922015-01-012227227810.5937/hpimj1502272M2334-94921502272MNew interventional neuroradiological procedures in Serbia: The direct costs of classical neurosurgical intervention in relation to the endovascular treatment of intracranial aneurysmsMajstorović Branislava M.0Milošević-Medenica Svetlana B.1Milaković Branko D.2Naumović Tamara S.3Center for Anesthesiology and Reanimatology, Clinical Centre of Serbia, BelgradeCenter for Radiology and Magnetic Resonance Imaging, Clinical Centre of Serbia, BelgradeCenter for Anesthesiology and Reanimatology, Clinical Centre of Serbia, Belgrade + Faculty of Medicine, University of Belgrade, BelgradeFaculty of Medicine, University of Belgrade, Belgrade + Institute of Medical Statistics and Informatics, BelgradeIntroduction: Intracranial aneurysms are one of the major causes of the neurosurgical morbidity and mortality. Each new therapeutic method, in relation to the standard one, generates high medical costs, as a rule. There have not been estimate of costs of treatment of intracranial aneurysms in Serbia. Objective: The aim of this study was to compare direct medical costs of clipping the neck of the aneurysm in relation to the new neuroradiological technique based on filling the aneurysmal sack with platinum coils and/or stenting the neck of the aneurysm. Methods: In a study approved by the Ethics committee of the Belgrade School of Medicine, we retrospectively measured the direct costs of treatment of bleeding and nonbleeding aneurysms at the Clinic of Neurosurgery, Clinical Centre of Serbia (CCS) in 2010. The study included a total of 300 patients divided in two groups: 1) study group included 99 patients with embolized aneurysms and 2) control group included 201 patients who were operated on by classical neurosurgical technique. Direct medical costs were calculated by the methodology of the State Health Care Insurance Fund. Analysis of results was performed using a software package SPSS. Results: Endovascular treatment was associated with 3% of adverse effects, lower mortality (2% vs. 2.9%), significantly shorter length of hospital stay (Z = - 8.566; p < 0.01), longer duration of anesthesia (226.7 to 195.2 minutes) and significantly higher costs (Z = - 12.475; p < 0.01) compared to neurosurgical treatment. A significant difference in costs was determined mainly by the price of embolization material, 328,169 RSD per patient (3,111€), and the number of resolved aneurysms (more than one, when the multiple aneurysms were treated). Conclusion: The procedural costs of embolization technique are high, as opposed to small number of hospital days. The readiness of the State Health Care Insurance Fund to pay for the costs of embolization should be approved following cost-utility analysis of both modalities, for the longer period of time.http://scindeks-clanci.ceon.rs/data/pdf/2334-9492/2015/2334-94921502272M.pdfintracranial aneurysmsembolizationneurosurgerydirect costs
spellingShingle Majstorović Branislava M.
Milošević-Medenica Svetlana B.
Milaković Branko D.
Naumović Tamara S.
New interventional neuroradiological procedures in Serbia: The direct costs of classical neurosurgical intervention in relation to the endovascular treatment of intracranial aneurysms
Hospital Pharmacology
intracranial aneurysms
embolization
neurosurgery
direct costs
title New interventional neuroradiological procedures in Serbia: The direct costs of classical neurosurgical intervention in relation to the endovascular treatment of intracranial aneurysms
title_full New interventional neuroradiological procedures in Serbia: The direct costs of classical neurosurgical intervention in relation to the endovascular treatment of intracranial aneurysms
title_fullStr New interventional neuroradiological procedures in Serbia: The direct costs of classical neurosurgical intervention in relation to the endovascular treatment of intracranial aneurysms
title_full_unstemmed New interventional neuroradiological procedures in Serbia: The direct costs of classical neurosurgical intervention in relation to the endovascular treatment of intracranial aneurysms
title_short New interventional neuroradiological procedures in Serbia: The direct costs of classical neurosurgical intervention in relation to the endovascular treatment of intracranial aneurysms
title_sort new interventional neuroradiological procedures in serbia the direct costs of classical neurosurgical intervention in relation to the endovascular treatment of intracranial aneurysms
topic intracranial aneurysms
embolization
neurosurgery
direct costs
url http://scindeks-clanci.ceon.rs/data/pdf/2334-9492/2015/2334-94921502272M.pdf
work_keys_str_mv AT majstorovicbranislavam newinterventionalneuroradiologicalproceduresinserbiathedirectcostsofclassicalneurosurgicalinterventioninrelationtotheendovasculartreatmentofintracranialaneurysms
AT milosevicmedenicasvetlanab newinterventionalneuroradiologicalproceduresinserbiathedirectcostsofclassicalneurosurgicalinterventioninrelationtotheendovasculartreatmentofintracranialaneurysms
AT milakovicbrankod newinterventionalneuroradiologicalproceduresinserbiathedirectcostsofclassicalneurosurgicalinterventioninrelationtotheendovasculartreatmentofintracranialaneurysms
AT naumovictamaras newinterventionalneuroradiologicalproceduresinserbiathedirectcostsofclassicalneurosurgicalinterventioninrelationtotheendovasculartreatmentofintracranialaneurysms