Relationships of Motor Changes with Cognitive and Neuropsychiatric Features in FMR1 Male Carriers Affected with Fragile X-Associated Tremor/Ataxia Syndrome

Relationships of Motor Changes with Cognitive and Neuropsychiatric Features in FMR1 Male Carriers Affected with Fragile X-Associated Tremor/Ataxia Syndrome

The premutation expansion of the Fragile X Messenger Ribonucleoprotein 1 (FMR1) gene on the X chromosome has been linked to a range of clinical and subclinical features. Nearly half of men with FMR1 premutation develop a neurodegenerative disorder; Fragile X-Associated Tremor/Ataxia Syndrome (FXTAS)...

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Bibliographic Details
Main Authors: Darren R. Hocking, Danuta Z. Loesch, Paige Stimpson, Flora Tassone, Anna Atkinson, Elsdon Storey
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Brain Sciences
Subjects:
FMR1 premutation
CGG repeats
FXTAS
motor scores
cognitive assessments
psychiatric measures
Online Access:https://www.mdpi.com/2076-3425/12/11/1549

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