Rocky Mountain spotted fever in an endemic area in Minas Gerais, Brazil

Only one species of spotted fever-group rickettsiae that is pathogenic for humans has been isolated in Brazil, where few physicians are familiar with this disease. In order to obtain information on tick-borne rickettsiosis, a study was performed in the County of Santa Cruz do Escalvado, State of Min...

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Main Authors: Elba Regina Sampaio de Lemos, Raimundo Diogo Machado, José Rodrigues Coura
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 1994-12-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761994000400001
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author Elba Regina Sampaio de Lemos
Raimundo Diogo Machado
José Rodrigues Coura
author_facet Elba Regina Sampaio de Lemos
Raimundo Diogo Machado
José Rodrigues Coura
author_sort Elba Regina Sampaio de Lemos
collection DOAJ
description Only one species of spotted fever-group rickettsiae that is pathogenic for humans has been isolated in Brazil, where few physicians are familiar with this disease. In order to obtain information on tick-borne rickettsiosis, a study was performed in the County of Santa Cruz do Escalvado, State of Minas Gerais, Brazil, where a fatal clinical case confirmed by specific immunofluorescence had been reported. Serum samples obtained from 679 humans and 96 dogs were tested by indirect immunofluorescence for detectable antibodies to spotted fever-group rickettsiae, the criterion for a positive result being a titer > or = 1:64. Seropositivity was detected in 7.14 of the humans sera examined and 13.68 of the dogs. We discuss the significance of these findings and formulate some questions, emphasizing the need for further investigation.
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spelling doaj.art-3ad445f4094b48c19d856820e51c7baf2023-09-03T07:25:05ZengFundação Oswaldo Cruz (FIOCRUZ)Memorias do Instituto Oswaldo Cruz0074-02761678-80601994-12-0189449750110.1590/S0074-02761994000400001Rocky Mountain spotted fever in an endemic area in Minas Gerais, BrazilElba Regina Sampaio de LemosRaimundo Diogo MachadoJosé Rodrigues CouraOnly one species of spotted fever-group rickettsiae that is pathogenic for humans has been isolated in Brazil, where few physicians are familiar with this disease. In order to obtain information on tick-borne rickettsiosis, a study was performed in the County of Santa Cruz do Escalvado, State of Minas Gerais, Brazil, where a fatal clinical case confirmed by specific immunofluorescence had been reported. Serum samples obtained from 679 humans and 96 dogs were tested by indirect immunofluorescence for detectable antibodies to spotted fever-group rickettsiae, the criterion for a positive result being a titer > or = 1:64. Seropositivity was detected in 7.14 of the humans sera examined and 13.68 of the dogs. We discuss the significance of these findings and formulate some questions, emphasizing the need for further investigation.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761994000400001spotted feverBrazilhumansdogs
spellingShingle Elba Regina Sampaio de Lemos
Raimundo Diogo Machado
José Rodrigues Coura
Rocky Mountain spotted fever in an endemic area in Minas Gerais, Brazil
Memorias do Instituto Oswaldo Cruz
spotted fever
Brazil
humans
dogs
title Rocky Mountain spotted fever in an endemic area in Minas Gerais, Brazil
title_full Rocky Mountain spotted fever in an endemic area in Minas Gerais, Brazil
title_fullStr Rocky Mountain spotted fever in an endemic area in Minas Gerais, Brazil
title_full_unstemmed Rocky Mountain spotted fever in an endemic area in Minas Gerais, Brazil
title_short Rocky Mountain spotted fever in an endemic area in Minas Gerais, Brazil
title_sort rocky mountain spotted fever in an endemic area in minas gerais brazil
topic spotted fever
Brazil
humans
dogs
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761994000400001
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