Comparison of Lipid Profile between People with Oral Lichen Planus and Healthy People
Introduction: Lichen planus is a relatively common chronic inflammatory mucocutaneous disease with unknown etiology and pathogenesis. Dyslipidemia caused by chronic inflammation results in the formation of atherosclerotic plaques which is associated with the risk of cardiovascular diseases. There is...
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| Format: | Article |
| Language: | fas |
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Mashhad University of Medical Sciences
2022-03-01
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| Series: | Journal of Mashhad Dental School |
| Online Access: | https://jmds.mums.ac.ir/article_19626_87ef4f9d268026e6b9f264f805f1dc4f.pdf |
| _version_ | 1811311715184279552 |
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| author | Fateme Arbabi-kalati pouya mobasheri |
| author_facet | Fateme Arbabi-kalati pouya mobasheri |
| author_sort | Fateme Arbabi-kalati |
| collection | DOAJ |
| description | Introduction: Lichen planus is a relatively common chronic inflammatory mucocutaneous disease with unknown etiology and pathogenesis. Dyslipidemia caused by chronic inflammation results in the formation of atherosclerotic plaques which is associated with the risk of cardiovascular diseases. There is a dearth of studies with conflicting results in this regard; therefore, the present study aimed to compare the lipid profile as a risk factor for cardiovascular disease between patients with oral lichen planus and healthy people.Materials and Methods: This case-control study was conducted in 2019. Firstly, the aim of the study was explained to the patients and written consent was obtained. Thereafter, the patients' blood pressure and body mass index (BMI) were recorded in the data collection form. The patients were referred to the laboratory to check their cholesterol (HDL, LDL) and triglyceride levels. Data were analyzed in SPSS software (version 18) using the Mann-Whitney U test to analyze the data and compare the indicators in the two groups.Results: The mean age scores of the participants were obtained at 46.7±16.9 and 41.5±10.1 years in the Liken Plan oral and control groups, respectively, and they did not differ significantly (P=0.59). There was a statistically significant difference between the two groups in terms of LDL and HDL, and the rates of LDL and HDL were higher in healthy people and OLP patients (P=0.036 and P=0.04, respectively); nonetheless, they were in the normal range in both groups.Conclusion: Dyslipidemia was normal in patients with OLP, and oral lichen planus did not appear to be a single risk factor for dyslipidemia. |
| first_indexed | 2024-04-13T10:23:47Z |
| format | Article |
| id | doaj.art-3ad576fcb8ef4740837cf9f903e445e4 |
| institution | Directory Open Access Journal |
| issn | 1560-9286 2008-2347 |
| language | fas |
| last_indexed | 2024-04-13T10:23:47Z |
| publishDate | 2022-03-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Journal of Mashhad Dental School |
| spelling | doaj.art-3ad576fcb8ef4740837cf9f903e445e42022-12-22T02:50:23ZfasMashhad University of Medical SciencesJournal of Mashhad Dental School1560-92862008-23472022-03-01461111610.22038/jmds.2022.57832.205119626Comparison of Lipid Profile between People with Oral Lichen Planus and Healthy PeopleFateme Arbabi-kalati0pouya mobasheri1Associate of Professor, Department of Oral Medicine, Oral and Dental Disease Research Center, Zahedan University of Medical Sciences, Zahedan, IranDentist, Zahedan, IranIntroduction: Lichen planus is a relatively common chronic inflammatory mucocutaneous disease with unknown etiology and pathogenesis. Dyslipidemia caused by chronic inflammation results in the formation of atherosclerotic plaques which is associated with the risk of cardiovascular diseases. There is a dearth of studies with conflicting results in this regard; therefore, the present study aimed to compare the lipid profile as a risk factor for cardiovascular disease between patients with oral lichen planus and healthy people.Materials and Methods: This case-control study was conducted in 2019. Firstly, the aim of the study was explained to the patients and written consent was obtained. Thereafter, the patients' blood pressure and body mass index (BMI) were recorded in the data collection form. The patients were referred to the laboratory to check their cholesterol (HDL, LDL) and triglyceride levels. Data were analyzed in SPSS software (version 18) using the Mann-Whitney U test to analyze the data and compare the indicators in the two groups.Results: The mean age scores of the participants were obtained at 46.7±16.9 and 41.5±10.1 years in the Liken Plan oral and control groups, respectively, and they did not differ significantly (P=0.59). There was a statistically significant difference between the two groups in terms of LDL and HDL, and the rates of LDL and HDL were higher in healthy people and OLP patients (P=0.036 and P=0.04, respectively); nonetheless, they were in the normal range in both groups.Conclusion: Dyslipidemia was normal in patients with OLP, and oral lichen planus did not appear to be a single risk factor for dyslipidemia.https://jmds.mums.ac.ir/article_19626_87ef4f9d268026e6b9f264f805f1dc4f.pdf |
| spellingShingle | Fateme Arbabi-kalati pouya mobasheri Comparison of Lipid Profile between People with Oral Lichen Planus and Healthy People Journal of Mashhad Dental School |
| title | Comparison of Lipid Profile between People with Oral Lichen Planus and Healthy People |
| title_full | Comparison of Lipid Profile between People with Oral Lichen Planus and Healthy People |
| title_fullStr | Comparison of Lipid Profile between People with Oral Lichen Planus and Healthy People |
| title_full_unstemmed | Comparison of Lipid Profile between People with Oral Lichen Planus and Healthy People |
| title_short | Comparison of Lipid Profile between People with Oral Lichen Planus and Healthy People |
| title_sort | comparison of lipid profile between people with oral lichen planus and healthy people |
| url | https://jmds.mums.ac.ir/article_19626_87ef4f9d268026e6b9f264f805f1dc4f.pdf |
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