Prediction of transcription factor bindings sites affected by SNPs located at the osteopontin promoter

This data contains information related to the research article entitled “Osteopontin splice variants and polymorphisms in Cancer Progression and Prognosis” [1]. Here, we describe an in silico analysis of transcription factors that could have altered binding to their DNA target sequence as a result o...

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Main Authors: Marco Antonio Briones-Orta, S. Eréndira Avendaño-Vázquez, Diana Ivette Aparicio-Bautista, Jason D. Coombes, Georg F. Weber, Wing-Kin Syn
Format: Article
Language:English
Published: Elsevier 2017-10-01
Series:Data in Brief
Online Access:http://www.sciencedirect.com/science/article/pii/S2352340917303591
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author Marco Antonio Briones-Orta
S. Eréndira Avendaño-Vázquez
Diana Ivette Aparicio-Bautista
Jason D. Coombes
Georg F. Weber
Wing-Kin Syn
author_facet Marco Antonio Briones-Orta
S. Eréndira Avendaño-Vázquez
Diana Ivette Aparicio-Bautista
Jason D. Coombes
Georg F. Weber
Wing-Kin Syn
author_sort Marco Antonio Briones-Orta
collection DOAJ
description This data contains information related to the research article entitled “Osteopontin splice variants and polymorphisms in Cancer Progression and Prognosis” [1]. Here, we describe an in silico analysis of transcription factors that could have altered binding to their DNA target sequence as a result of SNPs in the osteopontin gene promoter. We concentrated on SNPs associated with cancer risk and development. The analysis was performed with PROMO v3.0.2 software which incorporates TRANSFACT v6.4 of. We also present a figure depicting the putative transcription factor binding according to genotype.
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spelling doaj.art-3ad73710a6304cb286248b1bf6f5c6a52022-12-21T19:48:45ZengElsevierData in Brief2352-34092017-10-0114C53854210.1016/j.dib.2017.07.057Prediction of transcription factor bindings sites affected by SNPs located at the osteopontin promoterMarco Antonio Briones-Orta0S. Eréndira Avendaño-Vázquez1Diana Ivette Aparicio-Bautista2Jason D. Coombes3Georg F. Weber4Wing-Kin Syn5Regeneration and Repair, Institute of Hepatology, Foundation for Liver Research, London, United KingdomInstituto Nacional de Medicina Genómica, INMEGEN, Periférico Sur 4809, Ciudad de México 14610,. MéxicoInstituto Nacional de Medicina Genómica, INMEGEN, Periférico Sur 4809, Ciudad de México 14610,. MéxicoRegeneration and Repair, Institute of Hepatology, Foundation for Liver Research, London, United KingdomJames L. Winkle College of Pharmacy, University of Cincinnati Academic Health Center, Cincinnati, OH, United StatesRegeneration and Repair, Institute of Hepatology, Foundation for Liver Research, London, United KingdomThis data contains information related to the research article entitled “Osteopontin splice variants and polymorphisms in Cancer Progression and Prognosis” [1]. Here, we describe an in silico analysis of transcription factors that could have altered binding to their DNA target sequence as a result of SNPs in the osteopontin gene promoter. We concentrated on SNPs associated with cancer risk and development. The analysis was performed with PROMO v3.0.2 software which incorporates TRANSFACT v6.4 of. We also present a figure depicting the putative transcription factor binding according to genotype.http://www.sciencedirect.com/science/article/pii/S2352340917303591
spellingShingle Marco Antonio Briones-Orta
S. Eréndira Avendaño-Vázquez
Diana Ivette Aparicio-Bautista
Jason D. Coombes
Georg F. Weber
Wing-Kin Syn
Prediction of transcription factor bindings sites affected by SNPs located at the osteopontin promoter
Data in Brief
title Prediction of transcription factor bindings sites affected by SNPs located at the osteopontin promoter
title_full Prediction of transcription factor bindings sites affected by SNPs located at the osteopontin promoter
title_fullStr Prediction of transcription factor bindings sites affected by SNPs located at the osteopontin promoter
title_full_unstemmed Prediction of transcription factor bindings sites affected by SNPs located at the osteopontin promoter
title_short Prediction of transcription factor bindings sites affected by SNPs located at the osteopontin promoter
title_sort prediction of transcription factor bindings sites affected by snps located at the osteopontin promoter
url http://www.sciencedirect.com/science/article/pii/S2352340917303591
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