Piribedil-induced Reversible Pisa Syndrome in a Patient with Lewy Body Dementia
Pisa syndrome (PS) has been described for the first time as a side effect of neuroleptic treatment in patients with schizophrenia. After its first description, PS was reported in patients on dopamine receptor antagonists, cholinesterase inhibitors, and antidepressants. PS was also associated with ne...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Galenos Yayinevi
2021-06-01
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| Series: | Türk Nöroloji Dergisi |
| Subjects: | |
| Online Access: | https://tjn.org.tr/jvi.aspx?pdir=tjn&plng=eng&un=TJN-28000&look4= |
| _version_ | 1797917376826572800 |
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| author | Murat Mert Atmaca Başar Bilgiç Haşmet Hanağası |
| author_facet | Murat Mert Atmaca Başar Bilgiç Haşmet Hanağası |
| author_sort | Murat Mert Atmaca |
| collection | DOAJ |
| description | Pisa syndrome (PS) has been described for the first time as a side effect of neuroleptic treatment in patients with schizophrenia. After its first description, PS was reported in patients on dopamine receptor antagonists, cholinesterase inhibitors, and antidepressants. PS was also associated with neurodegenerative diseases such as Alzheimer’s disease, multiple system atrophy, and dementia of Lewy bodies (DLB). Dopaminergic treatment in Parkinson’s disease (PD) may also lead to PS in PD patients. Here, we report a patient with probable DLB who developed PS after the initiation of piribedil treatment. After cessation of piribedil, PS disappeared entirely. We want to highlight that PS related to dopaminergic treatment may be reversible, and like other dopamine agonists, piribedil has the potential to cause PS in patients with parkinsonism. |
| first_indexed | 2024-04-10T13:12:19Z |
| format | Article |
| id | doaj.art-3ad7a7828a1b4742a6336a10a5456228 |
| institution | Directory Open Access Journal |
| issn | 1309-2545 |
| language | English |
| last_indexed | 2024-04-10T13:12:19Z |
| publishDate | 2021-06-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Türk Nöroloji Dergisi |
| spelling | doaj.art-3ad7a7828a1b4742a6336a10a54562282023-02-15T16:12:32ZengGalenos YayineviTürk Nöroloji Dergisi1309-25452021-06-0127219219410.4274/tnd.2021.28000Piribedil-induced Reversible Pisa Syndrome in a Patient with Lewy Body DementiaMurat Mert Atmaca0https://orcid.org/0000-0003-2048-4930Başar Bilgiç1https://orcid.org/0000-0001-6032-0856Haşmet Hanağası2https://orcid.org/0000-0001-9645-7707Istanbul University, Istanbul Faculty of Medicine Hospital, Clinic of Neurology, Istanbul, TurkeyIstanbul University, Istanbul Faculty of Medicine Hospital, Clinic of Neurology, Istanbul, TurkeyIstanbul University, Istanbul Faculty of Medicine Hospital, Clinic of Neurology, Istanbul, TurkeyPisa syndrome (PS) has been described for the first time as a side effect of neuroleptic treatment in patients with schizophrenia. After its first description, PS was reported in patients on dopamine receptor antagonists, cholinesterase inhibitors, and antidepressants. PS was also associated with neurodegenerative diseases such as Alzheimer’s disease, multiple system atrophy, and dementia of Lewy bodies (DLB). Dopaminergic treatment in Parkinson’s disease (PD) may also lead to PS in PD patients. Here, we report a patient with probable DLB who developed PS after the initiation of piribedil treatment. After cessation of piribedil, PS disappeared entirely. We want to highlight that PS related to dopaminergic treatment may be reversible, and like other dopamine agonists, piribedil has the potential to cause PS in patients with parkinsonism.https://tjn.org.tr/jvi.aspx?pdir=tjn&plng=eng&un=TJN-28000&look4=parkinsonismpisa syndromepiribedildopamine agonists |
| spellingShingle | Murat Mert Atmaca Başar Bilgiç Haşmet Hanağası Piribedil-induced Reversible Pisa Syndrome in a Patient with Lewy Body Dementia Türk Nöroloji Dergisi parkinsonism pisa syndrome piribedil dopamine agonists |
| title | Piribedil-induced Reversible Pisa Syndrome in a Patient with Lewy Body Dementia |
| title_full | Piribedil-induced Reversible Pisa Syndrome in a Patient with Lewy Body Dementia |
| title_fullStr | Piribedil-induced Reversible Pisa Syndrome in a Patient with Lewy Body Dementia |
| title_full_unstemmed | Piribedil-induced Reversible Pisa Syndrome in a Patient with Lewy Body Dementia |
| title_short | Piribedil-induced Reversible Pisa Syndrome in a Patient with Lewy Body Dementia |
| title_sort | piribedil induced reversible pisa syndrome in a patient with lewy body dementia |
| topic | parkinsonism pisa syndrome piribedil dopamine agonists |
| url | https://tjn.org.tr/jvi.aspx?pdir=tjn&plng=eng&un=TJN-28000&look4= |
| work_keys_str_mv | AT muratmertatmaca piribedilinducedreversiblepisasyndromeinapatientwithlewybodydementia AT basarbilgic piribedilinducedreversiblepisasyndromeinapatientwithlewybodydementia AT hasmethanagası piribedilinducedreversiblepisasyndromeinapatientwithlewybodydementia |