Label-free quantitative proteomics analysis of producer and non-producer Chinese Hamsters Ovary (CHO) cells under ER stress conditions

Chinese Hamster Ovary (CHO) cells are the most commonly used host cell line used in the biopharmaceutical industry for the production of biotherapeutics. However, the lack of understanding of endoplasmic reticulum (ER) stress mechanisms involved in protein production, folding and secretion remains a...

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Bibliographic Details
Main Authors: David Ryan, Christiana-Kondylo Sideri, Michael Henry, Esen Efeoglu, Paula Meleady
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Current Research in Biotechnology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590262823000230