CXCL8 Up-Regulated LSECtin through AKT Signal and Correlates with the Immune Microenvironment Modulation in Colon Cancer

CXCL8 Up-Regulated LSECtin through AKT Signal and Correlates with the Immune Microenvironment Modulation in Colon Cancer

Background: The role of CXCL8 and LSECtin in colon cancer liver metastasis and immune checkpoint inhibitors (ICIs) treatment effect were widely recognized. However, the regulatory role of CXCL8 on LSECtin is still unclear. Methods: The expression of CXCL8 or LSECtin was analyzed by TCGA database, an...

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Bibliographic Details
Main Authors: Shaojun Fang, Xianshuo Cheng, Tao Shen, Jian Dong, Yunfeng Li, Zhenhui Li, Linghan Tian, Yangwei Zhang, Xueyan Pan, Zhengfeng Yin, Zhibin Yang
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Cancers
Subjects:
CXCL8
LSECtin
immune microenvironment
colon cancer
liver metastasis
Online Access:https://www.mdpi.com/2072-6694/14/21/5300

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