Adiposity reduces the risk of osteoporosis in Chinese rural population: the Henan rural cohort study
Abstract Background Adiposity plays a crucial role in the risk of osteoporosis. However, the impact of body fat distribution on the skeleton is contentious. The study was designed to explore the association of various adiposity indices with estimated bone mineral density (BMD) and the risk of osteop...
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| Format: | Article |
| Language: | English |
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BMC
2020-03-01
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| Series: | BMC Public Health |
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| Online Access: | http://link.springer.com/article/10.1186/s12889-020-8379-4 |
| _version_ | 1828894241338687488 |
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| author | Huiling Tian Jun Pan Dou Qiao Xiaokang Dong Ruiying Li Yikang Wang Runqi Tu Tanko Abdulai Xiaotian Liu Jian Hou Gongyuan Zhang Chongjian Wang |
| author_facet | Huiling Tian Jun Pan Dou Qiao Xiaokang Dong Ruiying Li Yikang Wang Runqi Tu Tanko Abdulai Xiaotian Liu Jian Hou Gongyuan Zhang Chongjian Wang |
| author_sort | Huiling Tian |
| collection | DOAJ |
| description | Abstract Background Adiposity plays a crucial role in the risk of osteoporosis. However, the impact of body fat distribution on the skeleton is contentious. The study was designed to explore the association of various adiposity indices with estimated bone mineral density (BMD) and the risk of osteoporosis based on body mass index (BMI), body fat percentage (BFP), waist circumference (WC), waist to hip ratio (WHR), waist to height ratio (WHtR), and visceral fat index (VFI). Methods A total of 8475 subjects derived from the Henan Rural Cohort Study were analyzed. The estimated BMD of study participants were measured by calcaneal quantitative ultrasound (QUS). Linear regression and binary logistic regression were performed to estimate the association of adiposity and the outcomes. Results The mean age of the study participants was 55.23 ± 11.09 years and 59.61% were women. The crude and age-standardized prevalence of high osteoporosis risk was 16.24 and 11.82%. Per unit increment in adiposity indices was associated with 0.005–0.021 g/cm2 increase in estimated BMD. The adjusted odds ratios (95% confidence interval) for high osteoporosis risk in per 1 SD increase of WC, WHR, WHtR, BMI, BFP, and VFI were 0.820 (0.748, 0.898), 0.872 (0.811, 0.938), 0.825 (0.765, 0.891), 0.798 (0.726, 0.878), 0.882 (0.800, 0.972), and 0.807 (0.732, 0.889), respectively. Stratified analyses indicated greater effects on individuals aged 55 years or older. Conclusions The adiposity indices have an inverse association with the risk of osteoporosis among Chinese rural population, especially in the elderly. |
| first_indexed | 2024-12-13T14:08:04Z |
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| id | doaj.art-3adbb0e1fcda4ae08d742fbce2d529ad |
| institution | Directory Open Access Journal |
| issn | 1471-2458 |
| language | English |
| last_indexed | 2024-12-13T14:08:04Z |
| publishDate | 2020-03-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Public Health |
| spelling | doaj.art-3adbb0e1fcda4ae08d742fbce2d529ad2022-12-21T23:42:34ZengBMCBMC Public Health1471-24582020-03-012011910.1186/s12889-020-8379-4Adiposity reduces the risk of osteoporosis in Chinese rural population: the Henan rural cohort studyHuiling Tian0Jun Pan1Dou Qiao2Xiaokang Dong3Ruiying Li4Yikang Wang5Runqi Tu6Tanko Abdulai7Xiaotian Liu8Jian Hou9Gongyuan Zhang10Chongjian Wang11Department of Epidemiology and Biostatistics, College of Public Health, Zhengzhou UniversityDepartment of Orthopaedic Surgery, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical UniversityDepartment of Epidemiology and Biostatistics, College of Public Health, Zhengzhou UniversityDepartment of Epidemiology and Biostatistics, College of Public Health, Zhengzhou UniversityDepartment of Epidemiology and Biostatistics, College of Public Health, Zhengzhou UniversityDepartment of Epidemiology and Biostatistics, College of Public Health, Zhengzhou UniversityDepartment of Epidemiology and Biostatistics, College of Public Health, Zhengzhou UniversityDepartment of Epidemiology and Biostatistics, College of Public Health, Zhengzhou UniversityDepartment of Epidemiology and Biostatistics, College of Public Health, Zhengzhou UniversityDepartment of Epidemiology and Biostatistics, College of Public Health, Zhengzhou UniversityDepartment of Epidemiology and Biostatistics, College of Public Health, Zhengzhou UniversityDepartment of Epidemiology and Biostatistics, College of Public Health, Zhengzhou UniversityAbstract Background Adiposity plays a crucial role in the risk of osteoporosis. However, the impact of body fat distribution on the skeleton is contentious. The study was designed to explore the association of various adiposity indices with estimated bone mineral density (BMD) and the risk of osteoporosis based on body mass index (BMI), body fat percentage (BFP), waist circumference (WC), waist to hip ratio (WHR), waist to height ratio (WHtR), and visceral fat index (VFI). Methods A total of 8475 subjects derived from the Henan Rural Cohort Study were analyzed. The estimated BMD of study participants were measured by calcaneal quantitative ultrasound (QUS). Linear regression and binary logistic regression were performed to estimate the association of adiposity and the outcomes. Results The mean age of the study participants was 55.23 ± 11.09 years and 59.61% were women. The crude and age-standardized prevalence of high osteoporosis risk was 16.24 and 11.82%. Per unit increment in adiposity indices was associated with 0.005–0.021 g/cm2 increase in estimated BMD. The adjusted odds ratios (95% confidence interval) for high osteoporosis risk in per 1 SD increase of WC, WHR, WHtR, BMI, BFP, and VFI were 0.820 (0.748, 0.898), 0.872 (0.811, 0.938), 0.825 (0.765, 0.891), 0.798 (0.726, 0.878), 0.882 (0.800, 0.972), and 0.807 (0.732, 0.889), respectively. Stratified analyses indicated greater effects on individuals aged 55 years or older. Conclusions The adiposity indices have an inverse association with the risk of osteoporosis among Chinese rural population, especially in the elderly.http://link.springer.com/article/10.1186/s12889-020-8379-4AdiposityBone mineral densityOsteoporosisRural population |
| spellingShingle | Huiling Tian Jun Pan Dou Qiao Xiaokang Dong Ruiying Li Yikang Wang Runqi Tu Tanko Abdulai Xiaotian Liu Jian Hou Gongyuan Zhang Chongjian Wang Adiposity reduces the risk of osteoporosis in Chinese rural population: the Henan rural cohort study BMC Public Health Adiposity Bone mineral density Osteoporosis Rural population |
| title | Adiposity reduces the risk of osteoporosis in Chinese rural population: the Henan rural cohort study |
| title_full | Adiposity reduces the risk of osteoporosis in Chinese rural population: the Henan rural cohort study |
| title_fullStr | Adiposity reduces the risk of osteoporosis in Chinese rural population: the Henan rural cohort study |
| title_full_unstemmed | Adiposity reduces the risk of osteoporosis in Chinese rural population: the Henan rural cohort study |
| title_short | Adiposity reduces the risk of osteoporosis in Chinese rural population: the Henan rural cohort study |
| title_sort | adiposity reduces the risk of osteoporosis in chinese rural population the henan rural cohort study |
| topic | Adiposity Bone mineral density Osteoporosis Rural population |
| url | http://link.springer.com/article/10.1186/s12889-020-8379-4 |
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