Conformational changes in the human Cx43/GJA1 gap junction channel visualized using cryo-EM

Conformational changes in the human Cx43/GJA1 gap junction channel visualized using cryo-EM

Gap junction intercellular channels (GJIChs) facilitate direct communication between adjacent cells. Here, authors provide high-resolution information on dynamic structural changes in Cx43 GJICh that are necessary to understand the gating mechanism.

Bibliographic Details
Main Authors:	Hyuk-Joon Lee, Hyung Jin Cha, Hyeongseop Jeong, Seu-Na Lee, Chang-Won Lee, Minsoo Kim, Jejoong Yoo, Jae-Sung Woo
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-02-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-023-36593-y

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