Toxoplasmic Infection in Pregnant Women from Cluj County and Neighbouring Area

Toxoplasmosis is an antropozoonosis very frequent in population as a benign usually asymptomatic disease. The problems are raised by the congenital form of this disease that may occur if the women acquire the parasite during pregnancy leading to congenital toxoplasmosis. In order to prevent congenit...

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Main Authors: Carmen A. COSTACHE, Ştefan I. ŢIGAN, Ioana COLOSI, Zoe COROIU
Format: Article
Language:English
Published: Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca 2008-12-01
Series:Applied Medical Informatics
Subjects:
Online Access:http://ami.info.umfcluj.ro/Full-text/AMI_23_2008/AMI(23)_031_036.pdf
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author Carmen A. COSTACHE
Ştefan I. ŢIGAN
Ioana COLOSI
Zoe COROIU
author_facet Carmen A. COSTACHE
Ştefan I. ŢIGAN
Ioana COLOSI
Zoe COROIU
author_sort Carmen A. COSTACHE
collection DOAJ
description Toxoplasmosis is an antropozoonosis very frequent in population as a benign usually asymptomatic disease. The problems are raised by the congenital form of this disease that may occur if the women acquire the parasite during pregnancy leading to congenital toxoplasmosis. In order to prevent congenital toxoplasmosis many countries have screening programs design to diagnose the acute infection during fertile age of female population. Our prospective serologic study over a selected group of 510 pregnant women in Cluj county area showed a 39 % prevalence of toxoplasmic infection among women of fertile age, with a predominance of acute toxoplasmic infection during first trimester of pregnancy (66.66%), representing the predominant cause of abortion in our study group. Annual infection risk for female population aged 20-33 years old is K = 0.67% in our geographic area. A 4 % of cases had IgM persistence for more than 1-year period, and another 7% demonstrate positive IgM along with positive IgG raising the possibility of persistency to 11% of cases. We find out that half of women address laboratory by their own initiative and we calculate that medium age of pregnant women with toxoplasmic immunity (positive IgG) was 28 years old.
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spelling doaj.art-3adea08aa5d8411098477401d65fa5972022-12-22T00:18:08ZengIuliu Hatieganu University of Medicine and Pharmacy, Cluj-NapocaApplied Medical Informatics1224-55932008-12-01233-43136Toxoplasmic Infection in Pregnant Women from Cluj County and Neighbouring AreaCarmen A. COSTACHEŞtefan I. ŢIGANIoana COLOSIZoe COROIUToxoplasmosis is an antropozoonosis very frequent in population as a benign usually asymptomatic disease. The problems are raised by the congenital form of this disease that may occur if the women acquire the parasite during pregnancy leading to congenital toxoplasmosis. In order to prevent congenital toxoplasmosis many countries have screening programs design to diagnose the acute infection during fertile age of female population. Our prospective serologic study over a selected group of 510 pregnant women in Cluj county area showed a 39 % prevalence of toxoplasmic infection among women of fertile age, with a predominance of acute toxoplasmic infection during first trimester of pregnancy (66.66%), representing the predominant cause of abortion in our study group. Annual infection risk for female population aged 20-33 years old is K = 0.67% in our geographic area. A 4 % of cases had IgM persistence for more than 1-year period, and another 7% demonstrate positive IgM along with positive IgG raising the possibility of persistency to 11% of cases. We find out that half of women address laboratory by their own initiative and we calculate that medium age of pregnant women with toxoplasmic immunity (positive IgG) was 28 years old.http://ami.info.umfcluj.ro/Full-text/AMI_23_2008/AMI(23)_031_036.pdfAntitoxoplasmic serologyPregnant womenToxoplasmosis annual infection riskIgM persistency.
spellingShingle Carmen A. COSTACHE
Ştefan I. ŢIGAN
Ioana COLOSI
Zoe COROIU
Toxoplasmic Infection in Pregnant Women from Cluj County and Neighbouring Area
Applied Medical Informatics
Antitoxoplasmic serology
Pregnant women
Toxoplasmosis annual infection risk
IgM persistency.
title Toxoplasmic Infection in Pregnant Women from Cluj County and Neighbouring Area
title_full Toxoplasmic Infection in Pregnant Women from Cluj County and Neighbouring Area
title_fullStr Toxoplasmic Infection in Pregnant Women from Cluj County and Neighbouring Area
title_full_unstemmed Toxoplasmic Infection in Pregnant Women from Cluj County and Neighbouring Area
title_short Toxoplasmic Infection in Pregnant Women from Cluj County and Neighbouring Area
title_sort toxoplasmic infection in pregnant women from cluj county and neighbouring area
topic Antitoxoplasmic serology
Pregnant women
Toxoplasmosis annual infection risk
IgM persistency.
url http://ami.info.umfcluj.ro/Full-text/AMI_23_2008/AMI(23)_031_036.pdf
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