Activity of Iranian Medicinal Herbs against Human Intestinal Parasites (HIP): A Systematic Review
Background and objectives: Intestinal parasitic infections are a major public health problem worldwide, especially in developing countries. It is estimated that around 3.5 billion people are infected with intestinal parasites. Human intestinal parasites (HIP) are clinically important due to broad ep...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Golestan University of Medical Sciences
2020-09-01
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| Series: | Medical Laboratory Journal |
| Subjects: | |
| Online Access: | http://mlj.goums.ac.ir/article-1-1249-en.html |
| _version_ | 1828774026568269824 |
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| author | Masoud Soosaraei Ahmad Daryani Shahabeddin Sarvi Mohamad Taghi Rahimi Mahdi Fakhar Hajar Ziaei Hezarjaribi Mehdi Sharif |
| author_facet | Masoud Soosaraei Ahmad Daryani Shahabeddin Sarvi Mohamad Taghi Rahimi Mahdi Fakhar Hajar Ziaei Hezarjaribi Mehdi Sharif |
| author_sort | Masoud Soosaraei |
| collection | DOAJ |
| description | Background and objectives: Intestinal parasitic infections are a major public health problem worldwide, especially in developing countries. It is estimated that around 3.5 billion people are infected with intestinal parasites. Human intestinal parasites (HIP) are clinically important due to broad epidemiological distribution, reinfection and drug resistance. In the last decades, bioactive compounds from herbs were used against a wide variety of microorganisms including parasites. We aimed to perform a systematic review on studies on the effects of medicinal herbs on HIPs in Iran.
Methods: Relevant scientific publications until April, 2015 were extracted from five English databases (PubMed, Google Scholar, Ebsco, Science Direct and Scopus) and four Persian databases (Magiran, Irandoc, IranMedex and the Scientific Information Database).
Results: A total of 18 papers and two dissertations met the inclusion criteria. Overall, 22 different plant extracts were used against Giardia lamblia, Entamoeba histolytica, Cryptosporidium and Hymenolepis nana. Based on the results, the extracts could exert time- and dose-dependent inhibitory effects against the tested HIPs. Five plants types including Allium, Chenopodium botrys, Carum copticum, F. asafoetida and Artemisia annua were able to completely inhibit the tested parasites, while Thymus vulgaris and A. paradoxum showed the lowest inhibitory effect (7%).
Conclusions: Given the findings, it is recommended to conduct in vivo studies on medicinal herbs with favorable in vitro effects against HIPs. |
| first_indexed | 2024-12-11T15:13:53Z |
| format | Article |
| id | doaj.art-3ae060ae85fd40539766a38e2e41ca22 |
| institution | Directory Open Access Journal |
| issn | 2538-4449 |
| language | English |
| last_indexed | 2024-12-11T15:13:53Z |
| publishDate | 2020-09-01 |
| publisher | Golestan University of Medical Sciences |
| record_format | Article |
| series | Medical Laboratory Journal |
| spelling | doaj.art-3ae060ae85fd40539766a38e2e41ca222022-12-22T01:00:39ZengGolestan University of Medical SciencesMedical Laboratory Journal2538-44492020-09-01145112Activity of Iranian Medicinal Herbs against Human Intestinal Parasites (HIP): A Systematic ReviewMasoud Soosaraei0Ahmad Daryani1Shahabeddin Sarvi2Mohamad Taghi Rahimi3Mahdi Fakhar4Hajar Ziaei Hezarjaribi5Mehdi Sharif6 Toxoplasmosis Research Center, Mazandaran University of Medical Sciences, Sari,Iran Toxoplasmosis Research Center, Mazandaran University of Medical Sciences, Sari,Iran Toxoplasmosis Research Center, Mazandaran University of Medical Sciences, Sari,Iran School of Medical Science, Shahroud University of Medical Sciences, Shahroud, Iran Toxoplasmosis Research Center, Mazandaran University of Medical Sciences, Sari,Iran Toxoplasmosis Research Center, Mazandaran University of Medical Sciences, Sari,Iran Toxoplasmosis Research Center, Mazandaran University of Medical Sciences, Sari,Iran Background and objectives: Intestinal parasitic infections are a major public health problem worldwide, especially in developing countries. It is estimated that around 3.5 billion people are infected with intestinal parasites. Human intestinal parasites (HIP) are clinically important due to broad epidemiological distribution, reinfection and drug resistance. In the last decades, bioactive compounds from herbs were used against a wide variety of microorganisms including parasites. We aimed to perform a systematic review on studies on the effects of medicinal herbs on HIPs in Iran. Methods: Relevant scientific publications until April, 2015 were extracted from five English databases (PubMed, Google Scholar, Ebsco, Science Direct and Scopus) and four Persian databases (Magiran, Irandoc, IranMedex and the Scientific Information Database). Results: A total of 18 papers and two dissertations met the inclusion criteria. Overall, 22 different plant extracts were used against Giardia lamblia, Entamoeba histolytica, Cryptosporidium and Hymenolepis nana. Based on the results, the extracts could exert time- and dose-dependent inhibitory effects against the tested HIPs. Five plants types including Allium, Chenopodium botrys, Carum copticum, F. asafoetida and Artemisia annua were able to completely inhibit the tested parasites, while Thymus vulgaris and A. paradoxum showed the lowest inhibitory effect (7%). Conclusions: Given the findings, it is recommended to conduct in vivo studies on medicinal herbs with favorable in vitro effects against HIPs.http://mlj.goums.ac.ir/article-1-1249-en.htmlintestinal parasitesherbal medicinesplant extractsin vitroin vivo |
| spellingShingle | Masoud Soosaraei Ahmad Daryani Shahabeddin Sarvi Mohamad Taghi Rahimi Mahdi Fakhar Hajar Ziaei Hezarjaribi Mehdi Sharif Activity of Iranian Medicinal Herbs against Human Intestinal Parasites (HIP): A Systematic Review Medical Laboratory Journal intestinal parasites herbal medicines plant extracts in vitro in vivo |
| title | Activity of Iranian Medicinal Herbs against Human Intestinal Parasites (HIP): A Systematic Review |
| title_full | Activity of Iranian Medicinal Herbs against Human Intestinal Parasites (HIP): A Systematic Review |
| title_fullStr | Activity of Iranian Medicinal Herbs against Human Intestinal Parasites (HIP): A Systematic Review |
| title_full_unstemmed | Activity of Iranian Medicinal Herbs against Human Intestinal Parasites (HIP): A Systematic Review |
| title_short | Activity of Iranian Medicinal Herbs against Human Intestinal Parasites (HIP): A Systematic Review |
| title_sort | activity of iranian medicinal herbs against human intestinal parasites hip a systematic review |
| topic | intestinal parasites herbal medicines plant extracts in vitro in vivo |
| url | http://mlj.goums.ac.ir/article-1-1249-en.html |
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