Convergent evolution of argonaute-2 slicer antagonism in two distinct insect RNA viruses.

Convergent evolution of argonaute-2 slicer antagonism in two distinct insect RNA viruses.

RNA interference (RNAi) is a major antiviral pathway that shapes evolution of RNA viruses. We show here that Nora virus, a natural Drosophila pathogen, is both a target and suppressor of RNAi. We detected viral small RNAs with a signature of Dicer-2 dependent small interfering RNAs in Nora virus inf...

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Bibliographic Details
Main Authors: Joël T van Mierlo, Alfred W Bronkhorst, Gijs J Overheul, Sajna A Sadanandan, Jens-Ola Ekström, Marco Heestermans, Dan Hultmark, Christophe Antoniewski, Ronald P van Rij
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3420963?pdf=render

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