Alteration of the Premature tRNA Landscape by Gammaherpesvirus Infection

Alteration of the Premature tRNA Landscape by Gammaherpesvirus Infection

ABSTRACT Transfer RNAs (tRNAs) are transcribed by RNA polymerase III (RNAPIII) and play a central role in decoding our genome, yet their expression and noncanonical function remain understudied. Many DNA tumor viruses enhance the activity of RNAPIII, yet whether infection alters tRNA expression is l...

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Bibliographic Details
Main Authors: Jessica M. Tucker, Aaron M. Schaller, Ian Willis, Britt A. Glaunsinger
Format: Article
Language:English
Published: American Society for Microbiology 2020-12-01
Series:mBio
Subjects:
RNA polymerase III
gammaherpesvirus
tRNA
Online Access:https://journals.asm.org/doi/10.1128/mBio.02664-20

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