Starting Point for Protocols on the Use of Hyperdiluted Calcium Hydroxylapatite (Radiesse®) for Optimizing Age-Related Biostimulation and Rejuvenation of Face, Neck, Décolletage and Hands: A Case Series Report
Enrico Massidda1,2 1Private Practice in Aesthetic Medicine, Milano, Cagliari, Italy; 2Member of Società Internazionale di Medicina Estetica, Rome, ItalyCorrespondence: Enrico Massidda, Email drenricomassidda@gmail.comAbstract: Radiesse® is a dermal filler made of calcium hydroxylapatite, a natural c...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2023-11-01
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| Series: | Clinical, Cosmetic and Investigational Dermatology |
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| Online Access: | https://www.dovepress.com/starting-point-for-protocols-on-the-use-of-hyperdiluted-calcium-hydrox-peer-reviewed-fulltext-article-CCID |
| _version_ | 1797447434839785472 |
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| author | Massidda E |
| author_facet | Massidda E |
| author_sort | Massidda E |
| collection | DOAJ |
| description | Enrico Massidda1,2 1Private Practice in Aesthetic Medicine, Milano, Cagliari, Italy; 2Member of Società Internazionale di Medicina Estetica, Rome, ItalyCorrespondence: Enrico Massidda, Email drenricomassidda@gmail.comAbstract: Radiesse® is a dermal filler made of calcium hydroxylapatite, a natural component of the human body, which, in diluted and hyperdiluted forms, promotes, unlike other fillers, neocollagenesis, neoelastinogenesis, fibroblast proliferation, and angiogenesis, leading to a long-term improved skin quality, elasticity, tightening, and firmness. This case series examined the use of Radiesse® (Merz, Frankfurt, Germany) for skin rejuvenation and regeneration through a long-lasting action of collagen biostimulation. The report explored for the first time the use of different dilution ratios of Radiesse® in 50 patients of varying ages and skin needs. By combining microboluses, tunneling, and/or fanning techniques, Radiesse® was superficially injected in different body regions, including the full-face, neck, décolletage, and hands. The treatment was effective in improving skin thickness, laxity, and wrinkles in 95% of 30– 40 year-olds, 80% of 40– 60 year-olds, and 70% of > 60 year-olds, with an average improvement of 81.6% for the general population. The treatment was well-tolerated with no significant adverse effects reported. The report also describes specific cases and includes pictures comparing the baseline condition to the changes obtained after different months and Radiesse® sessions. The patients reported a clear improvement in skin firmness and brightness, as well as a visible improvement in wrinkles’ appearance. This report found that diluting and hyperdiluting Radiesse® with flexible dilution ratios favoured a treatment’s individualization, providing improved skin quality, elasticity, tightening, and firmness, without volume augmentation. In conclusion, it highlights the versatility and flexibility of Radiesse® and emphasizes its efficacy and safety in skin rejuvenation and regeneration.Keywords: aesthetics, biostimulation, calcium hydroxylapatite, hyperdilution, Radiesse, skin rejuvenation |
| first_indexed | 2024-03-09T13:55:53Z |
| format | Article |
| id | doaj.art-3ae83546443b40f4bf42f2f82ffc5c82 |
| institution | Directory Open Access Journal |
| issn | 1178-7015 |
| language | English |
| last_indexed | 2024-03-09T13:55:53Z |
| publishDate | 2023-11-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Clinical, Cosmetic and Investigational Dermatology |
| spelling | doaj.art-3ae83546443b40f4bf42f2f82ffc5c822023-11-30T18:44:06ZengDove Medical PressClinical, Cosmetic and Investigational Dermatology1178-70152023-11-01Volume 163427343988581Starting Point for Protocols on the Use of Hyperdiluted Calcium Hydroxylapatite (Radiesse®) for Optimizing Age-Related Biostimulation and Rejuvenation of Face, Neck, Décolletage and Hands: A Case Series ReportMassidda EEnrico Massidda1,2 1Private Practice in Aesthetic Medicine, Milano, Cagliari, Italy; 2Member of Società Internazionale di Medicina Estetica, Rome, ItalyCorrespondence: Enrico Massidda, Email drenricomassidda@gmail.comAbstract: Radiesse® is a dermal filler made of calcium hydroxylapatite, a natural component of the human body, which, in diluted and hyperdiluted forms, promotes, unlike other fillers, neocollagenesis, neoelastinogenesis, fibroblast proliferation, and angiogenesis, leading to a long-term improved skin quality, elasticity, tightening, and firmness. This case series examined the use of Radiesse® (Merz, Frankfurt, Germany) for skin rejuvenation and regeneration through a long-lasting action of collagen biostimulation. The report explored for the first time the use of different dilution ratios of Radiesse® in 50 patients of varying ages and skin needs. By combining microboluses, tunneling, and/or fanning techniques, Radiesse® was superficially injected in different body regions, including the full-face, neck, décolletage, and hands. The treatment was effective in improving skin thickness, laxity, and wrinkles in 95% of 30– 40 year-olds, 80% of 40– 60 year-olds, and 70% of > 60 year-olds, with an average improvement of 81.6% for the general population. The treatment was well-tolerated with no significant adverse effects reported. The report also describes specific cases and includes pictures comparing the baseline condition to the changes obtained after different months and Radiesse® sessions. The patients reported a clear improvement in skin firmness and brightness, as well as a visible improvement in wrinkles’ appearance. This report found that diluting and hyperdiluting Radiesse® with flexible dilution ratios favoured a treatment’s individualization, providing improved skin quality, elasticity, tightening, and firmness, without volume augmentation. In conclusion, it highlights the versatility and flexibility of Radiesse® and emphasizes its efficacy and safety in skin rejuvenation and regeneration.Keywords: aesthetics, biostimulation, calcium hydroxylapatite, hyperdilution, Radiesse, skin rejuvenationhttps://www.dovepress.com/starting-point-for-protocols-on-the-use-of-hyperdiluted-calcium-hydrox-peer-reviewed-fulltext-article-CCIDaestheticsbiostimulationcalcium hydroxylapatitehyperdilutionradiesse®skin rejuvenation |
| spellingShingle | Massidda E Starting Point for Protocols on the Use of Hyperdiluted Calcium Hydroxylapatite (Radiesse®) for Optimizing Age-Related Biostimulation and Rejuvenation of Face, Neck, Décolletage and Hands: A Case Series Report Clinical, Cosmetic and Investigational Dermatology aesthetics biostimulation calcium hydroxylapatite hyperdilution radiesse® skin rejuvenation |
| title | Starting Point for Protocols on the Use of Hyperdiluted Calcium Hydroxylapatite (Radiesse®) for Optimizing Age-Related Biostimulation and Rejuvenation of Face, Neck, Décolletage and Hands: A Case Series Report |
| title_full | Starting Point for Protocols on the Use of Hyperdiluted Calcium Hydroxylapatite (Radiesse®) for Optimizing Age-Related Biostimulation and Rejuvenation of Face, Neck, Décolletage and Hands: A Case Series Report |
| title_fullStr | Starting Point for Protocols on the Use of Hyperdiluted Calcium Hydroxylapatite (Radiesse®) for Optimizing Age-Related Biostimulation and Rejuvenation of Face, Neck, Décolletage and Hands: A Case Series Report |
| title_full_unstemmed | Starting Point for Protocols on the Use of Hyperdiluted Calcium Hydroxylapatite (Radiesse®) for Optimizing Age-Related Biostimulation and Rejuvenation of Face, Neck, Décolletage and Hands: A Case Series Report |
| title_short | Starting Point for Protocols on the Use of Hyperdiluted Calcium Hydroxylapatite (Radiesse®) for Optimizing Age-Related Biostimulation and Rejuvenation of Face, Neck, Décolletage and Hands: A Case Series Report |
| title_sort | starting point for protocols on the use of hyperdiluted calcium hydroxylapatite radiesse reg for optimizing age related biostimulation and rejuvenation of face neck d eacute colletage and hands a case series report |
| topic | aesthetics biostimulation calcium hydroxylapatite hyperdilution radiesse® skin rejuvenation |
| url | https://www.dovepress.com/starting-point-for-protocols-on-the-use-of-hyperdiluted-calcium-hydrox-peer-reviewed-fulltext-article-CCID |
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