Biomass of ryegrass from field experiments: toward a cost-effective and efficient biosourced catalyst for the synthesis of Moclobemide

Lolium perenne L., a common plant perennial ryegrass from Europe, northern Africa and Asia, was selected to produce biomass under field conditions. The biomass of this nonfood crop was from a highly contaminated agricultural soil by potentially toxic metals (Cd, Pb and Zn) with the aim of maintainin...

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Main Authors: Marie Hechelski, Christophe Waterlot, Pierrick Dufrénoy, Brice Louvel, Adam Daïch, Alina Ghinet
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Green Chemistry Letters and Reviews
Subjects:
Online Access:http://dx.doi.org/10.1080/17518253.2020.1856943
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author Marie Hechelski
Christophe Waterlot
Pierrick Dufrénoy
Brice Louvel
Adam Daïch
Alina Ghinet
author_facet Marie Hechelski
Christophe Waterlot
Pierrick Dufrénoy
Brice Louvel
Adam Daïch
Alina Ghinet
author_sort Marie Hechelski
collection DOAJ
description Lolium perenne L., a common plant perennial ryegrass from Europe, northern Africa and Asia, was selected to produce biomass under field conditions. The biomass of this nonfood crop was from a highly contaminated agricultural soil by potentially toxic metals (Cd, Pb and Zn) with the aim of maintaining the agricultural vocation of these soils. In this perspective and in view of the metal concentration (Cd, Pb, Zn, macro- and micro-nutrients), the biomass of ryegrass was considered as a bio 'ore' resource and was used as the starting material for the preparation of contemporary biosourced catalysts. The heterogeneous catalyst from the current work was successfully used in the synthesis of Moclobemide, used to treat anxiety and major depressive episodes. Through this original approach, Moclobemide was synthesized in one step, in 80% yield under solvent-free conditions.
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spelling doaj.art-3aeb868108db40f9999e49af341e3ff62022-12-21T22:57:27ZengTaylor & Francis GroupGreen Chemistry Letters and Reviews1751-82531751-71922021-01-01141152210.1080/17518253.2020.18569431856943Biomass of ryegrass from field experiments: toward a cost-effective and efficient biosourced catalyst for the synthesis of MoclobemideMarie Hechelski0Christophe Waterlot1Pierrick Dufrénoy2Brice Louvel3Adam Daïch4Alina Ghinet5Univ. Lille, IMT Lille Douai, Univ. Artois, JUNIAUniv. Lille, IMT Lille Douai, Univ. Artois, JUNIATRD Health & Environment, Team Sustainable Chemistry, JUNIA, Ecole des Hautes Etudes d’IngénieurUniv. Lille, IMT Lille Douai, Univ. Artois, JUNIANormandie Univ., UNILEHAVRETRD Health & Environment, Team Sustainable Chemistry, JUNIA, Ecole des Hautes Etudes d’IngénieurLolium perenne L., a common plant perennial ryegrass from Europe, northern Africa and Asia, was selected to produce biomass under field conditions. The biomass of this nonfood crop was from a highly contaminated agricultural soil by potentially toxic metals (Cd, Pb and Zn) with the aim of maintaining the agricultural vocation of these soils. In this perspective and in view of the metal concentration (Cd, Pb, Zn, macro- and micro-nutrients), the biomass of ryegrass was considered as a bio 'ore' resource and was used as the starting material for the preparation of contemporary biosourced catalysts. The heterogeneous catalyst from the current work was successfully used in the synthesis of Moclobemide, used to treat anxiety and major depressive episodes. Through this original approach, Moclobemide was synthesized in one step, in 80% yield under solvent-free conditions.http://dx.doi.org/10.1080/17518253.2020.1856943field experimentryegrassbiosourced catalystmoclobemideaminolysis
spellingShingle Marie Hechelski
Christophe Waterlot
Pierrick Dufrénoy
Brice Louvel
Adam Daïch
Alina Ghinet
Biomass of ryegrass from field experiments: toward a cost-effective and efficient biosourced catalyst for the synthesis of Moclobemide
Green Chemistry Letters and Reviews
field experiment
ryegrass
biosourced catalyst
moclobemide
aminolysis
title Biomass of ryegrass from field experiments: toward a cost-effective and efficient biosourced catalyst for the synthesis of Moclobemide
title_full Biomass of ryegrass from field experiments: toward a cost-effective and efficient biosourced catalyst for the synthesis of Moclobemide
title_fullStr Biomass of ryegrass from field experiments: toward a cost-effective and efficient biosourced catalyst for the synthesis of Moclobemide
title_full_unstemmed Biomass of ryegrass from field experiments: toward a cost-effective and efficient biosourced catalyst for the synthesis of Moclobemide
title_short Biomass of ryegrass from field experiments: toward a cost-effective and efficient biosourced catalyst for the synthesis of Moclobemide
title_sort biomass of ryegrass from field experiments toward a cost effective and efficient biosourced catalyst for the synthesis of moclobemide
topic field experiment
ryegrass
biosourced catalyst
moclobemide
aminolysis
url http://dx.doi.org/10.1080/17518253.2020.1856943
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