Recent Trends in Curcumin-Containing Inorganic-Based Nanoparticles Intended for In Vivo Cancer Therapy
Curcumin is a natural compound that has been widely investigated thanks to its various biological properties, including antiproliferative. This molecule acts on different cancers such as lung, breast, pancreatic, colorectal, etc. However, the bioactive actions of curcumin have limitations when its p...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-01-01
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| Series: | Pharmaceutics |
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| Online Access: | https://www.mdpi.com/1999-4923/16/2/177 |
| _version_ | 1827342964136869888 |
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| author | Douglas Dourado Júlio Abreu Miranda Matheus Cardoso de Oliveira Danielle Teixeira Freire Francisco Humberto Xavier-Júnior Edgar Julian Paredes-Gamero Éverton do Nascimento Alencar |
| author_facet | Douglas Dourado Júlio Abreu Miranda Matheus Cardoso de Oliveira Danielle Teixeira Freire Francisco Humberto Xavier-Júnior Edgar Julian Paredes-Gamero Éverton do Nascimento Alencar |
| author_sort | Douglas Dourado |
| collection | DOAJ |
| description | Curcumin is a natural compound that has been widely investigated thanks to its various biological properties, including antiproliferative. This molecule acts on different cancers such as lung, breast, pancreatic, colorectal, etc. However, the bioactive actions of curcumin have limitations when its physicochemical properties compromise its pharmacological potential. As a therapeutic strategy against cancer, curcumin has been associated with inorganic nanoparticles. These nanocarriers are capable of delivering curcumin and offering physicochemical properties that synergistically enhance anticancer properties. This review highlights the different types of curcumin-based inorganic nanoparticles and discusses their physicochemical properties and in vivo anticancer activity in different models of cancer. |
| first_indexed | 2024-03-07T22:17:42Z |
| format | Article |
| id | doaj.art-3aec7c9f970c47ea82cdb9271a206b8e |
| institution | Directory Open Access Journal |
| issn | 1999-4923 |
| language | English |
| last_indexed | 2024-03-07T22:17:42Z |
| publishDate | 2024-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pharmaceutics |
| spelling | doaj.art-3aec7c9f970c47ea82cdb9271a206b8e2024-02-23T15:30:59ZengMDPI AGPharmaceutics1999-49232024-01-0116217710.3390/pharmaceutics16020177Recent Trends in Curcumin-Containing Inorganic-Based Nanoparticles Intended for In Vivo Cancer TherapyDouglas Dourado0Júlio Abreu Miranda1Matheus Cardoso de Oliveira2Danielle Teixeira Freire3Francisco Humberto Xavier-Júnior4Edgar Julian Paredes-Gamero5Éverton do Nascimento Alencar6Department of Immunology, Aggeu Magalhães Institute (IAM), Oswaldo Cruz Foundation (FIOCRUZ), Recife 50670-420, PE, BrazilDepartment of Pharmacy, Federal University of Rio Grande do Norte (UFRN), Natal 59010-180, RN, BrazilDepartment of Pharmacy, Federal University of Rio Grande do Norte (UFRN), Natal 59010-180, RN, BrazilCollege of Pharmaceutical Sciences, Food and Nutrition, Federal University of Mato Grosso do Sul (UFMS), Campo Grande 79070-900, MS, BrazilLaboratory of Pharmaceutical Biotechnology (BioTecFarm), Department of Pharmacy, Federal University of Paraíba (UFPB), João Pessoa 58051-900, PB, BrazilCollege of Pharmaceutical Sciences, Food and Nutrition, Federal University of Mato Grosso do Sul (UFMS), Campo Grande 79070-900, MS, BrazilCollege of Pharmaceutical Sciences, Food and Nutrition, Federal University of Mato Grosso do Sul (UFMS), Campo Grande 79070-900, MS, BrazilCurcumin is a natural compound that has been widely investigated thanks to its various biological properties, including antiproliferative. This molecule acts on different cancers such as lung, breast, pancreatic, colorectal, etc. However, the bioactive actions of curcumin have limitations when its physicochemical properties compromise its pharmacological potential. As a therapeutic strategy against cancer, curcumin has been associated with inorganic nanoparticles. These nanocarriers are capable of delivering curcumin and offering physicochemical properties that synergistically enhance anticancer properties. This review highlights the different types of curcumin-based inorganic nanoparticles and discusses their physicochemical properties and in vivo anticancer activity in different models of cancer.https://www.mdpi.com/1999-4923/16/2/177curcuminoidsnanotechnologypre-clinicaloncology |
| spellingShingle | Douglas Dourado Júlio Abreu Miranda Matheus Cardoso de Oliveira Danielle Teixeira Freire Francisco Humberto Xavier-Júnior Edgar Julian Paredes-Gamero Éverton do Nascimento Alencar Recent Trends in Curcumin-Containing Inorganic-Based Nanoparticles Intended for In Vivo Cancer Therapy Pharmaceutics curcuminoids nanotechnology pre-clinical oncology |
| title | Recent Trends in Curcumin-Containing Inorganic-Based Nanoparticles Intended for In Vivo Cancer Therapy |
| title_full | Recent Trends in Curcumin-Containing Inorganic-Based Nanoparticles Intended for In Vivo Cancer Therapy |
| title_fullStr | Recent Trends in Curcumin-Containing Inorganic-Based Nanoparticles Intended for In Vivo Cancer Therapy |
| title_full_unstemmed | Recent Trends in Curcumin-Containing Inorganic-Based Nanoparticles Intended for In Vivo Cancer Therapy |
| title_short | Recent Trends in Curcumin-Containing Inorganic-Based Nanoparticles Intended for In Vivo Cancer Therapy |
| title_sort | recent trends in curcumin containing inorganic based nanoparticles intended for in vivo cancer therapy |
| topic | curcuminoids nanotechnology pre-clinical oncology |
| url | https://www.mdpi.com/1999-4923/16/2/177 |
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