Micro/Nano Technologies for High-Density Retinal Implant
During the past decades, there have been leaps in the development of micro/nano retinal implant technologies, which is one of the emerging applications in neural interfaces to restore vision. However, higher feedthroughs within a limited space are needed for more complex electronic systems and preci...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2019-06-01
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| Series: | Micromachines |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-666X/10/6/419 |
| _version_ | 1819153106316820480 |
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| author | Qi Zeng Saisai Zhao Hangao Yang Yi Zhang Tianzhun Wu |
| author_facet | Qi Zeng Saisai Zhao Hangao Yang Yi Zhang Tianzhun Wu |
| author_sort | Qi Zeng |
| collection | DOAJ |
| description | During the past decades, there have been leaps in the development of micro/nano retinal implant technologies, which is one of the emerging applications in neural interfaces to restore vision. However, higher feedthroughs within a limited space are needed for more complex electronic systems and precise neural modulations. Active implantable medical electronics are required to have good electrical and mechanical properties, such as being small, light, and biocompatible, and with low power consumption and minimal immunological reactions during long-term implantation. For this purpose, high-density implantable packaging and flexible microelectrode arrays (fMEAs) as well as high-performance coating materials for retinal stimulation are crucial to achieve high resolution. In this review, we mainly focus on the considerations of the high-feedthrough encapsulation of implantable biomedical components to prolong working life, and fMEAs for different implant sites to deliver electrical stimulation to targeted retinal neuron cells. In addition, the functional electrode materials to achieve superior stimulation efficiency are also reviewed. The existing challenge and future research directions of micro/nano technologies for retinal implant are briefly discussed at the end of the review. |
| first_indexed | 2024-12-22T14:59:55Z |
| format | Article |
| id | doaj.art-3af16fc9190e45428aff1e412e5d9aed |
| institution | Directory Open Access Journal |
| issn | 2072-666X |
| language | English |
| last_indexed | 2024-12-22T14:59:55Z |
| publishDate | 2019-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Micromachines |
| spelling | doaj.art-3af16fc9190e45428aff1e412e5d9aed2022-12-21T18:22:08ZengMDPI AGMicromachines2072-666X2019-06-0110641910.3390/mi10060419mi10060419Micro/Nano Technologies for High-Density Retinal ImplantQi Zeng0Saisai Zhao1Hangao Yang2Yi Zhang3Tianzhun Wu4Shenzhen Institutes of Advanced Technology (SIAT), Chinese Academy of Sciences (CAS), Shenzhen 518055, ChinaShenzhen Institutes of Advanced Technology (SIAT), Chinese Academy of Sciences (CAS), Shenzhen 518055, ChinaShenzhen Institutes of Advanced Technology (SIAT), Chinese Academy of Sciences (CAS), Shenzhen 518055, ChinaShenzhen CAS-Envision Medical Technology Co. Ltd., Shenzhen 518100, ChinaShenzhen Institutes of Advanced Technology (SIAT), Chinese Academy of Sciences (CAS), Shenzhen 518055, ChinaDuring the past decades, there have been leaps in the development of micro/nano retinal implant technologies, which is one of the emerging applications in neural interfaces to restore vision. However, higher feedthroughs within a limited space are needed for more complex electronic systems and precise neural modulations. Active implantable medical electronics are required to have good electrical and mechanical properties, such as being small, light, and biocompatible, and with low power consumption and minimal immunological reactions during long-term implantation. For this purpose, high-density implantable packaging and flexible microelectrode arrays (fMEAs) as well as high-performance coating materials for retinal stimulation are crucial to achieve high resolution. In this review, we mainly focus on the considerations of the high-feedthrough encapsulation of implantable biomedical components to prolong working life, and fMEAs for different implant sites to deliver electrical stimulation to targeted retinal neuron cells. In addition, the functional electrode materials to achieve superior stimulation efficiency are also reviewed. The existing challenge and future research directions of micro/nano technologies for retinal implant are briefly discussed at the end of the review.https://www.mdpi.com/2072-666X/10/6/419retinal implanthigh-densityimplantable packagingmicroelectrode arraycoating |
| spellingShingle | Qi Zeng Saisai Zhao Hangao Yang Yi Zhang Tianzhun Wu Micro/Nano Technologies for High-Density Retinal Implant Micromachines retinal implant high-density implantable packaging microelectrode array coating |
| title | Micro/Nano Technologies for High-Density Retinal Implant |
| title_full | Micro/Nano Technologies for High-Density Retinal Implant |
| title_fullStr | Micro/Nano Technologies for High-Density Retinal Implant |
| title_full_unstemmed | Micro/Nano Technologies for High-Density Retinal Implant |
| title_short | Micro/Nano Technologies for High-Density Retinal Implant |
| title_sort | micro nano technologies for high density retinal implant |
| topic | retinal implant high-density implantable packaging microelectrode array coating |
| url | https://www.mdpi.com/2072-666X/10/6/419 |
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