Anoctamins and Calcium Signalling: An Obstacle to EGFR Targeted Therapy in Glioblastoma?

Anoctamins and Calcium Signalling: An Obstacle to EGFR Targeted Therapy in Glioblastoma?

Glioblastoma is the most common form of high-grade glioma in adults and has a poor survival rate with very limited treatment options. There have been no significant advancements in glioblastoma treatment in over 30 years. Epidermal growth factor receptor is upregulated in most glioblastoma tumours a...

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Bibliographic Details
Main Authors: Brittany Dewdney, Lauren Ursich, Emily V. Fletcher, Terrance G. Johns
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Cancers
Subjects:
glioblastoma
high-grade glioma
EGFR
anoctamins
ion channels
calcium signalling
Online Access:https://www.mdpi.com/2072-6694/14/23/5932

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