Effects of Haemodialysis on Anterior Segment Parameters of the Eye in Patients with Endstage Renal Disease: A Cross-sectional Study
Introduction: Ocular manifestations of Haemodialysis (HD) are one of the important causes of morbidity in End-stage Renal Disease (ESRD) patients. According to studies, the incidence rate of glaucoma in the dialysis group was higher than that in the non dialysis group. Angle-closure glaucoma was...
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| Format: | Article |
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JCDR Research and Publications Private Limited
2024-01-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| author | Kalyani Ravindra Lohokare Varsha Nitin Kulkarni Tejaswini Prashant Khandgave Poonam Kaur Nihar Garg Rishabh Shah |
| author_facet | Kalyani Ravindra Lohokare Varsha Nitin Kulkarni Tejaswini Prashant Khandgave Poonam Kaur Nihar Garg Rishabh Shah |
| author_sort | Kalyani Ravindra Lohokare |
| collection | DOAJ |
| description | Introduction: Ocular manifestations of Haemodialysis (HD) are
one of the important causes of morbidity in End-stage Renal
Disease (ESRD) patients. According to studies, the incidence
rate of glaucoma in the dialysis group was higher than that
in the non dialysis group. Angle-closure glaucoma was found
to be more common, which depends on anterior chamber
morphology.
Aim: To assess the effect of HD on Intraocular Pressure (IOP),
Anterior Chamber Depth (ACD), and Lens Thickness (LT) in
patients with ESRD.
Materials and Methods: This was a single-centre crosssectional observational study conducted in the Department of
Ophthalmology on 170 eyes of 87 patients undergoing HD for at
least three months. The study was conducted between October
2020 and October 2022 at the Dialysis Centre of Bharati Vidyapeeth
(DTU) Medical College and Hospital, Pune, Maharashtra, India.
These patients underwent ophthalmological evaluation pre- and
postdialysis. IOP, ACD, and LT were measured 30 minutes prior to
and 30 minutes after the HD session. The paired t-test was used
to compare differences in means, and a p-value of <0.05 was
considered significant.
Results: The mean age of the study participants was 57.63±11.95
years. There was a decrease in mean ACD by 0.08±0.29 mm
(p=0.0001) and an increase in mean LT by 0.06±0.42 mm
(p-value=0.0001) postdialysis. The changes in IOP were variable
and not statistically significant (p=0.45).
Conclusion: Postdialysis, a significant increase in LT was
observed corresponding to a decrease in ACD. Although the
change in IOP was variable, this change might be more significant
in pre-existing narrow-angle patients undergoing dialysis. As a
result, the present study underscores the urgency of refining
screening protocols for HD patients to effectively address these
identified ocular changes and associated risks. |
| first_indexed | 2024-03-08T15:59:23Z |
| format | Article |
| id | doaj.art-3af92cdc284e43adb3732afea7093da5 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-03-08T15:59:23Z |
| publishDate | 2024-01-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-3af92cdc284e43adb3732afea7093da52024-01-08T10:55:40ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2024-01-011801010410.7860/JCDR/2024/65269.18901Effects of Haemodialysis on Anterior Segment Parameters of the Eye in Patients with Endstage Renal Disease: A Cross-sectional StudyKalyani Ravindra Lohokare0Varsha Nitin Kulkarni1Tejaswini Prashant Khandgave2Poonam Kaur3Nihar Garg4Rishabh Shah5Resident, Department of Ophthalmology, Bharati Vidyapeeth Medical College, Pune, Maharashtra, India.Professor and Head, Department of Ophthalmology, Bharati Vidyapeeth Medical College, Pune, Maharashtra, India.Associate Professor, Department of Ophthalmology, Bharati Vidyapeeth Medical College, Pune, Maharashtra, India.Professor and Head, Department of Dialysis, Bharati Vidyapeeth Medical College, Pune, Maharashtra, India.Senior Resident, Department of Ophthalmology, Bharati Vidyapeeth Medical College, Pune, Maharashtra, India.Resident, Department of Ophthalmology, Bharati Vidyapeeth Medical College, Pune, Maharashtra, India.Introduction: Ocular manifestations of Haemodialysis (HD) are one of the important causes of morbidity in End-stage Renal Disease (ESRD) patients. According to studies, the incidence rate of glaucoma in the dialysis group was higher than that in the non dialysis group. Angle-closure glaucoma was found to be more common, which depends on anterior chamber morphology. Aim: To assess the effect of HD on Intraocular Pressure (IOP), Anterior Chamber Depth (ACD), and Lens Thickness (LT) in patients with ESRD. Materials and Methods: This was a single-centre crosssectional observational study conducted in the Department of Ophthalmology on 170 eyes of 87 patients undergoing HD for at least three months. The study was conducted between October 2020 and October 2022 at the Dialysis Centre of Bharati Vidyapeeth (DTU) Medical College and Hospital, Pune, Maharashtra, India. These patients underwent ophthalmological evaluation pre- and postdialysis. IOP, ACD, and LT were measured 30 minutes prior to and 30 minutes after the HD session. The paired t-test was used to compare differences in means, and a p-value of <0.05 was considered significant. Results: The mean age of the study participants was 57.63±11.95 years. There was a decrease in mean ACD by 0.08±0.29 mm (p=0.0001) and an increase in mean LT by 0.06±0.42 mm (p-value=0.0001) postdialysis. The changes in IOP were variable and not statistically significant (p=0.45). Conclusion: Postdialysis, a significant increase in LT was observed corresponding to a decrease in ACD. Although the change in IOP was variable, this change might be more significant in pre-existing narrow-angle patients undergoing dialysis. As a result, the present study underscores the urgency of refining screening protocols for HD patients to effectively address these identified ocular changes and associated risks.https://www.jcdr.net/articles/PDF/18901/65269_CE[Ra1]_F(IS)_QC&Ref(AN_SL)_PF1(VD_DK_OM)_PFA(VD_KM)_PN(KM).pdfanterior chamber depthend stage renal diseaseglaucomahaemodialysisintraocular pressurelens thickness |
| spellingShingle | Kalyani Ravindra Lohokare Varsha Nitin Kulkarni Tejaswini Prashant Khandgave Poonam Kaur Nihar Garg Rishabh Shah Effects of Haemodialysis on Anterior Segment Parameters of the Eye in Patients with Endstage Renal Disease: A Cross-sectional Study Journal of Clinical and Diagnostic Research anterior chamber depth end stage renal disease glaucoma haemodialysis intraocular pressure lens thickness |
| title | Effects of Haemodialysis on Anterior Segment Parameters of the Eye in Patients with Endstage Renal Disease: A Cross-sectional Study |
| title_full | Effects of Haemodialysis on Anterior Segment Parameters of the Eye in Patients with Endstage Renal Disease: A Cross-sectional Study |
| title_fullStr | Effects of Haemodialysis on Anterior Segment Parameters of the Eye in Patients with Endstage Renal Disease: A Cross-sectional Study |
| title_full_unstemmed | Effects of Haemodialysis on Anterior Segment Parameters of the Eye in Patients with Endstage Renal Disease: A Cross-sectional Study |
| title_short | Effects of Haemodialysis on Anterior Segment Parameters of the Eye in Patients with Endstage Renal Disease: A Cross-sectional Study |
| title_sort | effects of haemodialysis on anterior segment parameters of the eye in patients with endstage renal disease a cross sectional study |
| topic | anterior chamber depth end stage renal disease glaucoma haemodialysis intraocular pressure lens thickness |
| url | https://www.jcdr.net/articles/PDF/18901/65269_CE[Ra1]_F(IS)_QC&Ref(AN_SL)_PF1(VD_DK_OM)_PFA(VD_KM)_PN(KM).pdf |
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