CCN3, POSTN, and PTHLH as potential key regulators of genomic integrity and cellular survival in iPSCs

CCN3, POSTN, and PTHLH as potential key regulators of genomic integrity and cellular survival in iPSCs

Reprogramming human somatic cells into a pluripotent state, achieved through the activation of well-defined transcriptional factors known as OSKM factors, offers significant potential for regenerative medicine. While OSKM factors are a robust reprogramming method, efficiency remains a challenge, wit...

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Bibliographic Details
Main Authors: Nuha T. Swaidan, Nada H. Soliman, Ahmed T. Aboughalia, Toqa Darwish, Ruba O. Almeshal, Azhar A. Al-Khulaifi, Rowaida Z. Taha, Rania Alanany, Ahmed Y. Hussein, Salam Salloum-Asfar, Sara A. Abdulla, Abdallah M. Abdallah, Mohamed M. Emara
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Molecular Biosciences
Subjects:
iPSCs
ESCs
transcription factors
genomic integrity
cellular survival
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2024.1342011/full

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