Effects of Subretinal Gene Transfer at Different Time Points in a Mouse Model of Retinal Degeneration.

Effects of Subretinal Gene Transfer at Different Time Points in a Mouse Model of Retinal Degeneration.

Lysophosphatidylcholine acyltransferase 1 (LPCAT1) is necessary for photoreceptors to generate an important lipid component of their membranes. The absence of LPCAT1 results in early and rapid rod and cone degeneration. Retinal degeneration 11 (rd11) mice carry a mutation in the Lpcat1 gene, and are...

Full description

Bibliographic Details
Main Authors: Xufeng Dai, Hua Zhang, Juanjuan Han, Ying He, Yangyang Zhang, Yan Qi, Ji-Jing Pang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4882044?pdf=render

Similar Items

Similar Items