AHR signaling pathway mediates mitochondrial oxidative phosphorylation which leads to cytarabine resistance

AHR signaling pathway mediates mitochondrial oxidative phosphorylation which leads to cytarabine resistance

The aryl hydrocarbon receptor (AHR) has been identified as a significant driver of tumorigenesis. However, its clinical significance in acute myeloid leukemia (AML) remains largely unclear. In this study, RNA-Seq data from AML patients (bone marrow samples from 173 newly diagnosed AML patients) obta...

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Bibliographic Details
Main Authors: Jia Yan, LI Xiyu, Chen Lulu, Li Ling, Zhang Suzhen, Huang Wenhui, Zhang Hao
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2024-02-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
AHR expression
AML
mitochondrial oxidative phosphorylation
cytarabine resistance
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2024022

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