Application of multi-modal imaging technology to optimize radiotherapy of microscopic lymph nodes for head and neck squamous cell carcinoma
Multi-modal imaging technology was used to screen the cervical microlymph nodes of patients with head and neck squamous cell carcinoma. Based on the pathological results, radiotherapy was optimized to improve the quality of life of patients. CT or magnetic resonance imaging (MRI) examination before...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | zho |
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Science Press
2023-06-01
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| Series: | Fushe yanjiu yu fushe gongyi xuebao |
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| Online Access: | http://www.fs.sinap.ac.cn/thesisDetails#10.11889/j.1000-3436.2023-0002&lang=zh |
| _version_ | 1797782053337432064 |
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| author | DONG Fang TAO Fali XUE Jincai XIN Yuanchun LU Yun ZHANG Li GUAN Ling GAO Liying WANG Jun LIU Qinjiang |
| author_facet | DONG Fang TAO Fali XUE Jincai XIN Yuanchun LU Yun ZHANG Li GUAN Ling GAO Liying WANG Jun LIU Qinjiang |
| author_sort | DONG Fang |
| collection | DOAJ |
| description | Multi-modal imaging technology was used to screen the cervical microlymph nodes of patients with head and neck squamous cell carcinoma. Based on the pathological results, radiotherapy was optimized to improve the quality of life of patients. CT or magnetic resonance imaging (MRI) examination before radiotherapy was performed in 36 patients with head and neck squamous cell carcinoma. Fifty-one microlymph nodes with ≤1 cm diameter were selected. Following the ultrasonic detection of relevant indicators, ultrasound-guided puncture biopsy was performed to confirm the pathology. Based on the multi-modal evaluation results, the target area and plan of radiotherapy was confirmed. We evaluated the dose to organs at risk before and after target optimization. The difference in the detection results was compared, and the 3-year local control rate of the lymph node region of interest was observed. The Dmean and V30 of the parotid (left and right) and submandibular gland (left and right) and the V50 of the mandibular gland (left and right) had significant differences before and after optimization in the microlymph node target area of the neck (p<0.05). After 3 years of follow-up, four patients had cervical lymph node recurrence in the high-dose irradiated field. The recurrence rate was 11.11%, and no local recurrence was observed in the microlymph node area of interest. Thus, multi-modal imaging technology is a safe and reliable method to further optimize radiotherapy target planning to distinguish between benign and malignant cervical microlymph nodes of head and neck squamous cell carcinoma. |
| first_indexed | 2024-03-13T00:05:37Z |
| format | Article |
| id | doaj.art-3b05d7d298df494f909ad67a073df86e |
| institution | Directory Open Access Journal |
| issn | 1000-3436 |
| language | zho |
| last_indexed | 2024-03-13T00:05:37Z |
| publishDate | 2023-06-01 |
| publisher | Science Press |
| record_format | Article |
| series | Fushe yanjiu yu fushe gongyi xuebao |
| spelling | doaj.art-3b05d7d298df494f909ad67a073df86e2023-07-13T03:05:50ZzhoScience PressFushe yanjiu yu fushe gongyi xuebao1000-34362023-06-0141303030603030610.11889/j.1000-3436.2023-00021000-3436（2023）03-0071-10Application of multi-modal imaging technology to optimize radiotherapy of microscopic lymph nodes for head and neck squamous cell carcinomaDONG Fang0TAO Fali1XUE Jincai2XIN Yuanchun3LU Yun4ZHANG Li5GUAN Ling6GAO Liying7WANG Jun8LIU Qinjiang9Department of radiotherapy, Gansu Province Cancer Hospital, Lanzhou 730050, ChinaDepartment of radiotherapy, Gansu Province Cancer Hospital, Lanzhou 730050, ChinaDepartment of Head and Neck Surgery, Gansu Province Cancer Hospital, Lanzhou 730050, ChinaDepartment of radiotherapy, Gansu Province Cancer Hospital, Lanzhou 730050, ChinaDepartment of Function, Gansu Province Cancer Hospital, Lanzhou 730050, ChinaDepartment of Function, Gansu Province Cancer Hospital, Lanzhou 730050, ChinaDepartment of Function, Gansu Province Cancer Hospital, Lanzhou 730050, ChinaDepartment of radiotherapy, Gansu Province Cancer Hospital, Lanzhou 730050, ChinaDepartment of Head and Neck Surgery, Gansu Province Cancer Hospital, Lanzhou 730050, ChinaDepartment of Head and Neck Surgery, Gansu Province Cancer Hospital, Lanzhou 730050, ChinaMulti-modal imaging technology was used to screen the cervical microlymph nodes of patients with head and neck squamous cell carcinoma. Based on the pathological results, radiotherapy was optimized to improve the quality of life of patients. CT or magnetic resonance imaging (MRI) examination before radiotherapy was performed in 36 patients with head and neck squamous cell carcinoma. Fifty-one microlymph nodes with ≤1 cm diameter were selected. Following the ultrasonic detection of relevant indicators, ultrasound-guided puncture biopsy was performed to confirm the pathology. Based on the multi-modal evaluation results, the target area and plan of radiotherapy was confirmed. We evaluated the dose to organs at risk before and after target optimization. The difference in the detection results was compared, and the 3-year local control rate of the lymph node region of interest was observed. The Dmean and V30 of the parotid (left and right) and submandibular gland (left and right) and the V50 of the mandibular gland (left and right) had significant differences before and after optimization in the microlymph node target area of the neck (p<0.05). After 3 years of follow-up, four patients had cervical lymph node recurrence in the high-dose irradiated field. The recurrence rate was 11.11%, and no local recurrence was observed in the microlymph node area of interest. Thus, multi-modal imaging technology is a safe and reliable method to further optimize radiotherapy target planning to distinguish between benign and malignant cervical microlymph nodes of head and neck squamous cell carcinoma.http://www.fs.sinap.ac.cn/thesisDetails#10.11889/j.1000-3436.2023-0002&lang=zhhead and neck squamous cell carcinomamicrolymph noderadiotherapy |
| spellingShingle | DONG Fang TAO Fali XUE Jincai XIN Yuanchun LU Yun ZHANG Li GUAN Ling GAO Liying WANG Jun LIU Qinjiang Application of multi-modal imaging technology to optimize radiotherapy of microscopic lymph nodes for head and neck squamous cell carcinoma Fushe yanjiu yu fushe gongyi xuebao head and neck squamous cell carcinoma microlymph node radiotherapy |
| title | Application of multi-modal imaging technology to optimize radiotherapy of microscopic lymph nodes for head and neck squamous cell carcinoma |
| title_full | Application of multi-modal imaging technology to optimize radiotherapy of microscopic lymph nodes for head and neck squamous cell carcinoma |
| title_fullStr | Application of multi-modal imaging technology to optimize radiotherapy of microscopic lymph nodes for head and neck squamous cell carcinoma |
| title_full_unstemmed | Application of multi-modal imaging technology to optimize radiotherapy of microscopic lymph nodes for head and neck squamous cell carcinoma |
| title_short | Application of multi-modal imaging technology to optimize radiotherapy of microscopic lymph nodes for head and neck squamous cell carcinoma |
| title_sort | application of multi modal imaging technology to optimize radiotherapy of microscopic lymph nodes for head and neck squamous cell carcinoma |
| topic | head and neck squamous cell carcinoma microlymph node radiotherapy |
| url | http://www.fs.sinap.ac.cn/thesisDetails#10.11889/j.1000-3436.2023-0002&lang=zh |
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