Metabolome and transcriptome analysis on muscle of sporadic inclusion body myositis

Metabolome and transcriptome analysis on muscle of sporadic inclusion body myositis

Abstract Objective Sporadic inclusion body myositis (sIBM) is the most common acquired myopathy in patients older than 50 years of age. sIBM is hardly responds to any immunosuppressing theraphies, and its pathophysiology remains elusive. This study aims to explore pathogenic pathways underlying sIBM...

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Main Authors: Ayuka Murakami, Seiya Noda, Tomoyuki Kazuta, Satoko Hirano, Seigo Kimura, Hirotaka Nakanishi, Koji Matsuo, Koyo Tsujikawa, Madoka Iida, Haruki Koike, Kazuma Sakamoto, Yuichiro Hara, Satoshi Kuru, Kenji Kadomatsu, Teppei Shimamura, Tomoo Ogi, Masahisa Katsuno
Format: Article
Language:English
Published: Wiley 2022-10-01
Series:Annals of Clinical and Translational Neurology
Online Access:https://doi.org/10.1002/acn3.51657

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